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Immunology & Microbiology Journal Club

The Immunology & Microbiology Journal Club is the central unifying course for the concentration.  It meets at noon on Thursdays during the fall semester in R2-265.

Schedule:

Date Presenter Reviewer Paper
Aug-28 Organizational Meeting
Sep-4 Ying Yi Zheng Ramya Sivakumar Greenlee-Wacker MC, Rigby KM, Kobayashi SD, Porter AR, DeLeo FR, Nauseef WM.  Phagocytosis of Staphylococcus aureus by human neutrophils prevents macrophage efferocytosis and induces programmed necrosis. J Immunol. 2014 May 15;192(10):4709-17.
Sep-11 Geoffrey Rogers Lauren Gay Raj DK, Nixon CP, Nixon CE, Dvorin JD, DiPetrillo CG, Pond-Tor S, Wu HW, Jolly G, Pischel L, Lu A, Michelow IC, Cheng L, Conteh S, McDonald EA, Absalon S, Holte SE, Friedman JF, Fried M, Duffy PE, Kurtis JD. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection. Science. 2014 May 23;344(6186):871-7
Sep-18 Christina Graves Justin Kasper Wang YY, Kannan A, Nunn KL, Murphy MA, Subramani DB, Moench T, Cone R, Lai SK.  IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections.  Mucosal Immunol. 2014 Sep;7(5):1036-44. (PDF not available to UF, see Dr. Chang for reprint)
Sep-25 Katrina Grau Adit Dhummakupt Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature. 2014 Aug 29.
Oct-2 Mehmet Kara David Holder Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K, Bailey AG, Laughlin AL, Boucher JL, Wherry EJ, Bushman FD, Allen JE, Virgin HW, Artis D. Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation. Science. 2014 Aug 1;345(6196):578-82.
Oct-9 Adrienne Gauna Ryan Chastain-Gross RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Trobaugh DW, Gardner CL, Sun C, Haddow, AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. Nature 20014 Feb 13; 506 (7487):245-8.
Oct-16 Rotation 1 presentations
Oct-23 Ramya Sivakumar Brittney Newby Chen F, Wu W, Millman A, Craft JF, Chen E, Patel N, Boucher JL, Urban JF Jr, Kim CC, Gause WC. Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion. Nat Immunol. 2014 Oct;15(10):938-46.
Oct-30 Heather Drew Jared Taylor Iijima N, Iwasaki A. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells. Science. 2014 Aug 28. pii: 1257530. [Epub ahead of print]
Nov-6 David Brice Jian Li Lahaye X, Satoh T, Gentili M, Cerboni S, Conrad C, Hurbain I, El Marjou A, Lacabaratz C, Lelièvre JD, Manel N. The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells. Immunity. 2013 Dec 12;39(6):1132-42.
Nov-13 Emily Feldman Pritesh Desai Waisberg M, Molina-Cruz A, Mizurini DM, Gera N, Sousa BC, Ma D, Leal AC, Gomes T, Kotsyfakis M, Ribeiro JM, Lukszo J, Reiter K, Porcella SF, Oliveira CJ, Monteiro RQ, Barillas-Mury C, Pierce SK, Francischetti IM. Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis. PLoS Pathog. 2014 Sep 11;10(9):e1004338.
Nov-20 Alicia Chechele Zachary Moye Karo JM, Schatz DG, Sun JC. The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells. Cell. 2014 Sep 25;159(1):94-107.
Nov-27 Thanksgiving
Dec-4 Rotation 2 presentations

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