Andrew J Bryant

Andrew J Bryant,

AST PROF

Department: MD-PULMONARY MEDICINE
Business Phone: (352) 273-8737

Publications

2021
CHK yourself, before you wreck yourself: targeting the DNA damage response in secondary pulmonary hypertension.
Thorax. [DOI] 10.1136/thoraxjnl-2021-217882. [PMID] 34417351.
2021
Emergency myelopoiesis contributes to immune cell exhaustion and pulmonary vascular remodelling.
British journal of pharmacology. 178(1):187-202 [DOI] 10.1111/bph.14945. [PMID] 31793661.
2021
Idiopathic pulmonary fibrosis and pulmonary hypertension: Heracles meets the Hydra.
British journal of pharmacology. 178(1):172-186 [DOI] 10.1111/bph.15036. [PMID] 32128790.
2021
Likelihood-based tests for detecting circadian rhythmicity and differential circadian patterns in transcriptomic applications.
Briefings in bioinformatics. [DOI] 10.1093/bib/bbab224. [PMID] 34117739.
2021
The Third Man: DNA sensing as espionage in pulmonary vascular health and disease.
Pulmonary circulation. 11(1) [DOI] 10.1177/2045894021996574. [PMID] 33738095.
2020
Hepatocyte nuclear factor 4α negatively regulates connective tissue growth factor during liver regeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34(4):4970-4983 [DOI] 10.1096/fj.201902382R. [PMID] 32057145.
2019
A checkpoint on innate myeloid cells in pulmonary arterial hypertension.
Pulmonary circulation. 9(1) [DOI] 10.1177/2045894018823528. [PMID] 30562157.
2019
Chemokine signaling axis between endothelial and myeloid cells regulates development of pulmonary hypertension associated with pulmonary fibrosis and hypoxia.
American journal of physiology. Lung cellular and molecular physiology. 317(4):L434-L444 [DOI] 10.1152/ajplung.00156.2019. [PMID] 31364370.
2018
Involvement of Microglial Cells in Hypoxia-induced Pulmonary Hypertension.
American journal of respiratory cell and molecular biology. 59(2):271-273 [DOI] 10.1165/rcmb.2018-0042LE. [PMID] 30067089.
2018
Myeloid-Derived Suppressor Cells and Pulmonary Hypertension.
International journal of molecular sciences. 19(8) [DOI] 10.3390/ijms19082277. [PMID] 30081463.
2018
Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension.
American journal of respiratory cell and molecular biology. 58(2):170-180 [DOI] 10.1165/rcmb.2017-0214OC. [PMID] 28862882.
2018
rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling.
Frontiers in physiology. 9 [DOI] 10.3389/fphys.2018.00271. [PMID] 29731719.
2018
Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells.
Respiratory research. 19(1) [DOI] 10.1186/s12931-018-0861-5. [PMID] 30165855.
2018
Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension.
Frontiers in physiology. 9 [DOI] 10.3389/fphys.2018.00138. [PMID] 29535639.
2016
“A small leak will sink a great ship”: hypoxia-inducible factor and group III pulmonary hypertension.
Receptors & clinical investigation. 3(1) [PMID] 27446973.
View on: PubMed
2016
Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology. 310(3):L249-62 [DOI] 10.1152/ajplung.00258.2015. [PMID] 26637636.
2015
Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis.
Pulmonary circulation. 5(4):681-90 [DOI] 10.1086/683811. [PMID] 26697175.
2013
Alcohol intolerance associated with Hodgkin lymphoma.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 185(8) [DOI] 10.1503/cmaj.120974. [PMID] 23091182.
2013
β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.
American journal of respiratory and critical care medicine. 187(6):630-9 [DOI] 10.1164/rccm.201205-0972OC. [PMID] 23306543.
2012
Through a glass, darkly.
Archives of internal medicine. 172(13):985-6 [DOI] 10.1001/archinternmed.2012.2765. [PMID] 22777628.
2006
Anesthetic preconditioning with sevoflurane does not protect the spinal cord after an ischemic-reperfusion injury in the rat.
Anesthesia and analgesia. 102(5):1341-7 [PMID] 16632806.
View on: PubMed
2006
The degree of atherosclerosis in the descending aorta does not predict poor in-hospital outcome after surgery requiring cardiopulmonary bypass.
Journal of cardiothoracic and vascular anesthesia. 20(2):149-55 [PMID] 16616652.
View on: PubMed

Grants

Aug 2020 ACTIVE
Myeloid cell senescence in the development of pulmonary hypertension
Role: Principal Investigator
Funding: BAYER HEALTHCARE PHARMACEUTICALS
Apr 2020 ACTIVE
Role of ADAM17 in MDSC-Mediated Development of Pulmonary Hypertension
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jan 2020 ACTIVE
Involvement of Neuroinflammation in Pulmonary Hypertension
Role: Other
Funding: AMER HEART ASSOCIATION
Aug 2019 ACTIVE
Role of CXCR2-mediated cell trafficking in pulmonary vascular remodeling
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2018 – Jan 2020
Role of myeloid-derived suppressor cells in pulmonary hypertension associated with pulmonary fibrosis
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2018 – Jun 2021
Role of MDSCs in pulmonary hypertension associated with pulmonary fibrosis
Role: Principal Investigator
Funding: PARKER B FRANCIS FELLOWSHIP FOU
Jul 2017 – Dec 2019
Role of CXCR2-mediated cell trafficking in pulmonary hypertension
Role: Principal Investigator
Funding: AMER LUNG ASSO
Jun 2017 – Dec 2019
Role of myeloid-derived suppressor cell trafficking in development of pulmonary hypertension
Role: Principal Investigator
Funding: GILEAD SCIENCES
Apr 2017 – Mar 2018
Together: Transforming and Translating Discovery to Improve Health
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Jan 2017 – Dec 2018
Role of myeloid-derived suppressor cell trafficking in development of pulmonary hypertension
Role: Principal Investigator
Funding: UF FOU via LANDENBERGER RES FOU, MARGARET Q.
Apr 2016 – Mar 2017
TOGETHER: TRANSFORMING AND TRANSLATING DISCOVERY TO IMPROVE ,HEALTH ,
Role: Project Manager
Funding: NATL INST OF HLTH NCATS
Jun 2001 ACTIVE
01040902
Role: Project Manager
Funding: GRIFOLS WORLDWIDE OPERATIONS LTD

Contact Details

Phones:
Business:
(352) 273-8737
Emails: