John P Aris

John P Aris, PhD

Aso Professor

Department: MD-ANATOMY
Business Phone: (352) 273-6868
Business Email: johnaris@ufl.edu

Teaching Profile

Courses Taught
2019-2023
GMS5057 Medical Cell Biology
2013-2014,2016-2023
GMS6001 Fundamentals of Biomedical Sciences I
2012-2023
BMS6031 Foundations of Med
2020-2022
DEN5121 Biochm Molec Cell Bio
2011-2018,2020-2021
DEN5210 Dev Biol Psychosoc 1
2020-2021
PAS5022C Gross/Radiograph Anat
2020-2022
BMS6632 Endo and Reproduction
2014,2016-2020,2020-2022
GMS6421 Cell Biology
2017-2022
BMS4136C Human Histology
2013-2022
DEN5126C Histology
2014-2017,2019
BCH7410 Advanced Gene Regulation
2007-2008,2010-2017,2015-2021,2017-2022,2019-2022,2021-2022
GMS6063 Cell Biology of Aging
2015-2016,2018
GMS6607C Musculoskeletal Systems
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS7979 Advanced Research
2018
VME7980 Research for Doctoral Dissertation
2015,2018-2021,2021-2023
BMS6638C Kidney & Urinary Tract
2010-2012,2014-2018,2016-2022,2022
GMS6062 Protein Trafficking
2018
BMS6300 Fund Micro and Immuno
2006-2008,2010-2016,2013-2023,2016-2023,2021-2023
GMS6635 Organization of Cells and Tissues
2011-2012,2014-2016,2016
DEN6416C Basic Sciences Rev
2016
GMS6644 Apoptosis
2016
GMS6940 Supervised Teaching
2013-2015
GMS5630 Medical Histology
2013-2014
GMS6622 Mitochondrial Biology in Aging and Disease
2014,2021-2023
GMS6692 Research Conference in Anatomy and Cell Biology
2013
GMS6690 Molecular Cell Biology Journal Club
2006-2008,2011
GMS6642 Morphogen Organ Sys 1
2006-2008,2011
GMS6643 Morphogen Organ Sys 2
2009-2011
BMS6110C Cell and Tissue Biol
2021
PAS5020 Intro to Medicine 2
2021
BMS6816 Cancer Bio Clin Oncol
2021
GMS6003 Fundamentals of Graduate Research and Professional Development
2022
GMS6691 Special Topics in Cell Biology and Anatomy

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-6475-064X

Publications

2022
The enduring legacy of Marie Curie: impacts of radium in 21st century radiological and medical sciences
International Journal of Radiation Biology. 98(3):267-275 [DOI] 10.1080/09553002.2022.2027542.
2020
Dosimetric considerations of 99mTc-MDP uptake within the epiphyseal plates of the long bones of pediatric patients
Physics in Medicine & Biology. 65(23) [DOI] 10.1088/1361-6560/abb1db.
2015
A moonlighting metabolic protein influences repair at DNA double-stranded breaks.
Nucleic acids research. 43(3):1646-58 [DOI] 10.1093/nar/gku1405. [PMID] 25628362.
2013
Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.
Experimental gerontology. 48(10):1107-19 [DOI] 10.1016/j.exger.2013.01.006. [PMID] 23337777.
2012
Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae.
Sub-cellular biochemistry. 57:161-86 [DOI] 10.1007/978-94-007-2561-4_8. [PMID] 22094422.
2012
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy. 8(4):445-544 [PMID] 22966490.
2011
The UF family of hybrid phantoms of the developing human fetus for computational radiation dosimetry.
Physics in medicine and biology. 56(15):4839-79 [DOI] 10.1088/0031-9155/56/15/014. [PMID] 21765203.
2010
Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae.
Molecular and cellular biochemistry. 333(1-2):99-108 [DOI] 10.1007/s11010-009-0209-z. [PMID] 19618123.
2010
Gingival RAGE expression in calorie-restricted versus ad libitum-fed rats.
Journal of periodontology. 81(10):1481-7 [DOI] 10.1902/jop.2010.100019. [PMID] 20572766.
2010
New insights into the role of mitochondria in aging: mitochondrial dynamics and more.
Journal of cell science. 123(Pt 15):2533-42 [DOI] 10.1242/jcs.070490. [PMID] 20940129.
2009
An image-based skeletal tissue model for the ICRP reference newborn.
Physics in medicine and biology. 54(14):4497-531 [DOI] 10.1088/0031-9155/54/14/009. [PMID] 19556686.
2009
Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae.
Aging cell. 8(4):353-69 [DOI] 10.1111/j.1474-9726.2009.00469.x. [PMID] 19302372.
2009
Autophagy is required for extension of yeast chronological life span by rapamycin.
Autophagy. 5(6):847-9 [PMID] 19458476.
2008
Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus.
Eukaryotic cell. 7(4):575-83 [DOI] 10.1128/EC.00412-07. [PMID] 18296619.
2006
Loc1p is required for efficient assembly and nuclear export of the 60S ribosomal subunit.
Molecular genetics and genomics : MGG. 276(4):369-77 [PMID] 16871394.
2006
Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast.
Molecular and cellular biology. 26(10):3889-901 [PMID] 16648483.
2005
2-micron circle plasmids do not reduce yeast life span.
FEMS microbiology letters. 250(2):245-51 [PMID] 16085372.
2005
Resurrecting ancestral alcohol dehydrogenases from yeast.
Nature genetics. 37(6):630-5 [PMID] 15864308.
2003
Plasmid accumulation reduces life span in Saccharomyces cerevisiae.
The Journal of biological chemistry. 278(43):41607-17 [PMID] 12904293.
2002
The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function.
The Journal of biological chemistry. 277(41):38409-15 [PMID] 12163484.
2001
Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.
Nucleic acids research. 29(14):2938-49 [PMID] 11452019.
2001
Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.
Nucleic acids research. 29(14):2927-37 [PMID] 11452018.
2000
Comparative spatial localization of protein-A-tagged and authentic yeast nuclear pore complex proteins by immunogold electron microscopy.
Journal of structural biology. 129(2-3):295-305 [PMID] 10806080.
2000
Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae.
Biochimica et biophysica acta. 1463(2):477-82 [PMID] 10675524.
2000
Multiple growth factor induction of a murine early response gene that complements a lethal defect in yeast ribosome biogenesis.
The Journal of biological chemistry. 275(18):13835-41 [PMID] 10788506.
1999
Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.
Genetics. 151(1):57-75 [PMID] 9872948.
1999
Transcription factor UAF, expansion and contraction of ribosomal DNA (rDNA) repeats, and RNA polymerase switch in transcription of yeast rDNA.
Molecular and cellular biology. 19(12):8559-69 [PMID] 10567580.
1998
Isolation of nuclei and nucleoli from the yeast Saccharomyces cerevisiae.
Methods in cell biology. 53:33-46 [PMID] 9348503.
1998
Mutational analysis of the structure and localization of the nucleolus in the yeast Saccharomyces cerevisiae.
The Journal of cell biology. 143(1):23-34 [PMID] 9763418.
1998
NCL1, a novel gene for a non-essential nuclear protein in Saccharomyces cerevisiae.
Gene. 220(1-2):109-17 [PMID] 9767141.
1998
Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast.
The Journal of biological chemistry. 273(26):16453-63 [PMID] 9632712.
1997
A Drosophila Tpr protein homolog is localized both in the extrachromosomal channel network and to nuclear pore complexes.
Journal of cell science. 110 ( Pt 8):927-44 [PMID] 9152019.
1997
Homocitrate synthase is located in the nucleus in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry. 272(16):10839-46 [PMID] 9099739.
1997
Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast.
Molecular and cellular biology. 17(1):378-88 [PMID] 8972218.
1994
Molecular analysis of mercury-induced antinucleolar antibodies in H-2S mice.
Journal of immunology (Baltimore, Md. : 1950). 152(2):667-75 [PMID] 8283044.
1994
Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker.
The Journal of cell biology. 127(6 Pt 2):1799-813 [PMID] 7806561.
1993
Molecular and biochemical characterization of a recombinant human PKC-delta family member.
Biochimica et biophysica acta. 1174(2):171-81 [PMID] 8357834.
1991
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera.
Proceedings of the National Academy of Sciences of the United States of America. 88(3):931-5 [PMID] 1846968.
1991
Isolation of yeast nuclei.
Methods in enzymology. 194:735-49 [PMID] 2005821.
1990
Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.
The Journal of biological chemistry. 265(4):2209-15 [PMID] 2298745.
1989
Yeast nuclear envelope proteins cross react with an antibody against mammalian pore complex proteins.
The Journal of cell biology. 108(6):2059-67 [PMID] 2661560.
1988
Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein.
The Journal of cell biology. 107(1):17-31 [PMID] 3292539.
1985
The beta subunit of the Escherichia coli ATP synthase exhibits a tight membrane binding property.
Biochemical and biophysical research communications. 128(1):155-62 [PMID] 2859019.
1985
The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore.
The Journal of biological chemistry. 260(20):11207-15 [PMID] 2863271.
1983
Cross-linking and labeling of the Escherichia coli F1F0-ATP synthase reveal a compact hydrophilic portion of F0 close to an F1 catalytic subunit.
The Journal of biological chemistry. 258(23):14599-609 [PMID] 6315730.

Grants

Mar 2022 ACTIVE
Multi-Scale Evaluation and Mitigation of Toxicities Following Internal Radionuclide Contamination
Role: Co-Investigator
Funding: NORTHWESTERN UNIV via NATL INST OF HLTH NIAID
Sep 2021 ACTIVE
Aligning Dosimetry and Biomarkers of Lung Injury with Prophylaxis and Mitigation of Damage from Radionuclides and Metals
Role: Co-Investigator
Funding: NORTHWESTERN UNIV via US ARMY MED RES ACQUISITION

Education

Postdoctoral Fellowships
1991 · Rockefeller University
PhD (Biological Sciences)
1985 · Stanford University
BS (Chemistry & Biology)
1979 · Jacksonville University

Contact Details

Phones:
Business:
(352) 273-6868
Emails:
Business:
johnaris@ufl.edu
Addresses:
Business Mailing:
HEALTH SCIENCE CENTER RM D2-32A
1395 CENTER DR
DEPARTMENT OF ANATOMY AND CELL BIOLOGY
GAINESVILLE FL 32610
Business Street:
HEALTH SCIENCE CENTER RM D2-32A
1395 CENTER DR
DEPARTMENT OF ANATOMY AND CELL BIOLOGY
GAINESVILLE FL 32610