John P Aris

John P Aris, PhD

Associate Professor

Department: MD-ANATOMY
Business Phone: (352) 273-6868
Business Email: johnaris@ufl.edu

Teaching Profile

Courses Taught
2019-2024
GMS5057 Medical Cell Biology
2013-2014,2016-2024
GMS6001 Fundamentals of Biomedical Sciences I
2012-2024
BMS6031 Foundations of Med
2020-2023
DEN5121 Biochm Molec Cell Bio
2011-2018,2020-2023,2023
DEN5210 Dev Biol Psychosoc 1
2020-2021
PAS5022C Gross/Radiograph Anat
2020-2024
BMS6632 Endo and Reproduction
2014,2016-2020,2020-2024
GMS6421 Cell Biology
2017-2024
BMS4136C Human Histology
2013-2024
DEN5126C Histology
2014-2017,2019
BCH7410 Advanced Gene Regulation
2007-2008,2010-2017,2015-2021,2017-2023,2019-2023,2021-2023
GMS6063 Cell Biology of Aging
2015-2016,2018
GMS6607C Musculoskeletal Systems
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS7979 Advanced Research
2018
VME7980 Research for Doctoral Dissertation
2015,2018-2021,2021-2023
BMS6638C Kidney & Urinary Tract
2010-2012,2014-2018,2016-2022,2022
GMS6062 Protein Trafficking
2018
BMS6300 Fund Micro and Immuno
2006-2008,2010-2016,2013-2024,2016-2024,2021-2024
GMS6635 Organization of Cells and Tissues
2011-2012,2014-2016,2016
DEN6416C Basic Sciences Rev
2016
GMS6644 Apoptosis
2016
GMS6940 Supervised Teaching
2013-2015
GMS5630 Medical Histology
2013-2014
GMS6622 Mitochondrial Biology in Aging and Disease
2014,2021-2024
GMS6692 Research Conference in Anatomy and Cell Biology
2013
GMS6690 Molecular Cell Biology Journal Club
2006-2008,2011
GMS6642 Morphogen Organ Sys 1
2006-2008,2011
GMS6643 Morphogen Organ Sys 2
2009-2011
BMS6110C Cell and Tissue Biol
2021
PAS5020 Intro to Medicine 2
2021,2024
BMS6816 Cancer Bio Clin Oncol
2021
GMS6003 Fundamentals of Graduate Research and Professional Development
2022-2024
GMS6691 Special Topics in Cell Biology and Anatomy
2023-2024
BMS6635 Derm and Msk
2023-2024
BMS6020 Clinical Neuroscience
2024
BMS6642 The Resp Sys Hlth
2024
BMS6633 The Cv System

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-6475-064X

Publications

2022
The enduring legacy of Marie Curie: impacts of radium in 21st century radiological and medical sciences
International Journal of Radiation Biology. 98(3):267-275 [DOI] 10.1080/09553002.2022.2027542. [PMID] 35030065.
2020
Dosimetric considerations of99mTc-MDP uptake within the epiphyseal plates of the long bones of pediatric patients
Physics in Medicine & Biology. 65(23) [DOI] 10.1088/1361-6560/abb1db.
2015
A moonlighting metabolic protein influences repair at DNA double-stranded breaks.
Nucleic acids research. 43(3):1646-58 [DOI] 10.1093/nar/gku1405. [PMID] 25628362.
2013
Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.
Experimental gerontology. 48(10):1107-19 [DOI] 10.1016/j.exger.2013.01.006. [PMID] 23337777.
2012
Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae.
Sub-cellular biochemistry. 57:161-86 [DOI] 10.1007/978-94-007-2561-4_8. [PMID] 22094422.
2012
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy. 8(4):445-544 [PMID] 22966490.
2011
The UF family of hybrid phantoms of the developing human fetus for computational radiation dosimetry.
Physics in medicine and biology. 56(15):4839-79 [DOI] 10.1088/0031-9155/56/15/014. [PMID] 21765203.
2010
Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae.
Molecular and cellular biochemistry. 333(1-2):99-108 [DOI] 10.1007/s11010-009-0209-z. [PMID] 19618123.
2010
Gingival RAGE expression in calorie-restricted versus ad libitum-fed rats.
Journal of periodontology. 81(10):1481-7 [DOI] 10.1902/jop.2010.100019. [PMID] 20572766.
2010
New insights into the role of mitochondria in aging: mitochondrial dynamics and more.
Journal of cell science. 123(Pt 15):2533-42 [DOI] 10.1242/jcs.070490. [PMID] 20940129.
2009
An image-based skeletal tissue model for the ICRP reference newborn.
Physics in medicine and biology. 54(14):4497-531 [DOI] 10.1088/0031-9155/54/14/009. [PMID] 19556686.
2009
Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae.
Aging cell. 8(4):353-69 [DOI] 10.1111/j.1474-9726.2009.00469.x. [PMID] 19302372.
2009
Autophagy is required for extension of yeast chronological life span by rapamycin.
Autophagy. 5(6):847-9 [PMID] 19458476.
2008
Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus.
Eukaryotic cell. 7(4):575-83 [DOI] 10.1128/EC.00412-07. [PMID] 18296619.
2006
Loc1p is required for efficient assembly and nuclear export of the 60S ribosomal subunit.
Molecular genetics and genomics : MGG. 276(4):369-77 [PMID] 16871394.
2006
Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast.
Molecular and cellular biology. 26(10):3889-901 [PMID] 16648483.
2005
2-micron circle plasmids do not reduce yeast life span.
FEMS microbiology letters. 250(2):245-51 [PMID] 16085372.
2005
Resurrecting ancestral alcohol dehydrogenases from yeast.
Nature genetics. 37(6):630-5 [PMID] 15864308.
2003
Plasmid accumulation reduces life span in Saccharomyces cerevisiae.
The Journal of biological chemistry. 278(43):41607-17 [PMID] 12904293.
2002
The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function.
The Journal of biological chemistry. 277(41):38409-15 [PMID] 12163484.
2001
Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae.
Nucleic acids research. 29(14):2938-49 [PMID] 11452019.
2001
Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.
Nucleic acids research. 29(14):2927-37 [PMID] 11452018.
2000
Comparative spatial localization of protein-A-tagged and authentic yeast nuclear pore complex proteins by immunogold electron microscopy.
Journal of structural biology. 129(2-3):295-305 [PMID] 10806080.
2000
Expression and subcellular localization of a membrane protein related to Hsp30p in Saccharomyces cerevisiae.
Biochimica et biophysica acta. 1463(2):477-82 [PMID] 10675524.
2000
Multiple growth factor induction of a murine early response gene that complements a lethal defect in yeast ribosome biogenesis.
The Journal of biological chemistry. 275(18):13835-41 [PMID] 10788506.
1999
Saccharomyces cerevisiae Mod5p-II contains sequences antagonistic for nuclear and cytosolic locations.
Genetics. 151(1):57-75 [PMID] 9872948.
1999
Transcription factor UAF, expansion and contraction of ribosomal DNA (rDNA) repeats, and RNA polymerase switch in transcription of yeast rDNA.
Molecular and cellular biology. 19(12):8559-69 [PMID] 10567580.
1998
Isolation of nuclei and nucleoli from the yeast Saccharomyces cerevisiae.
Methods in cell biology. 53:33-46 [PMID] 9348503.
1998
Mutational analysis of the structure and localization of the nucleolus in the yeast Saccharomyces cerevisiae.
The Journal of cell biology. 143(1):23-34 [PMID] 9763418.
1998
NCL1, a novel gene for a non-essential nuclear protein in Saccharomyces cerevisiae.
Gene. 220(1-2):109-17 [PMID] 9767141.
1998
Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast.
The Journal of biological chemistry. 273(26):16453-63 [PMID] 9632712.
1997
A Drosophila Tpr protein homolog is localized both in the extrachromosomal channel network and to nuclear pore complexes.
Journal of cell science. 110 ( Pt 8):927-44 [PMID] 9152019.
1997
Homocitrate synthase is located in the nucleus in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry. 272(16):10839-46 [PMID] 9099739.
1997
Nop2p is required for pre-rRNA processing and 60S ribosome subunit synthesis in yeast.
Molecular and cellular biology. 17(1):378-88 [PMID] 8972218.
1994
Molecular analysis of mercury-induced antinucleolar antibodies in H-2S mice.
Journal of immunology (Baltimore, Md. : 1950). 152(2):667-75 [PMID] 8283044.
1994
Yeast NOP2 encodes an essential nucleolar protein with homology to a human proliferation marker.
The Journal of cell biology. 127(6 Pt 2):1799-813 [PMID] 7806561.
1993
Molecular and biochemical characterization of a recombinant human PKC-delta family member.
Biochimica et biophysica acta. 1174(2):171-81 [PMID] 8357834.
1991
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera.
Proceedings of the National Academy of Sciences of the United States of America. 88(3):931-5 [PMID] 1846968.
1991
Isolation of yeast nuclei.
Methods in enzymology. 194:735-49 [PMID] 2005821.
1990
Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.
The Journal of biological chemistry. 265(4):2209-15 [PMID] 2298745.
1989
Yeast nuclear envelope proteins cross react with an antibody against mammalian pore complex proteins.
The Journal of cell biology. 108(6):2059-67 [PMID] 2661560.
1988
Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein.
The Journal of cell biology. 107(1):17-31 [PMID] 3292539.
1985
The beta subunit of the Escherichia coli ATP synthase exhibits a tight membrane binding property.
Biochemical and biophysical research communications. 128(1):155-62 [PMID] 2859019.
1985
The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore.
The Journal of biological chemistry. 260(20):11207-15 [PMID] 2863271.
1983
Cross-linking and labeling of the Escherichia coli F1F0-ATP synthase reveal a compact hydrophilic portion of F0 close to an F1 catalytic subunit.
The Journal of biological chemistry. 258(23):14599-609 [PMID] 6315730.

Grants

Sep 2023 ACTIVE
Imaging, Dosimetry and Radiobiology for a-particle Emitter Radiopharmaceutical Therapy
Role: Co-Investigator
Funding: JOHNS HOPKINS UNIVERSITY via NATL INST OF HLTH NCI
Mar 2022 ACTIVE
Multi-Scale Evaluation and Mitigation of Toxicities Following Internal Radionuclide Contamination
Role: Co-Investigator
Funding: NORTHWESTERN UNIV via NATL INST OF HLTH NIAID
Sep 2021 ACTIVE
Aligning Dosimetry and Biomarkers of Lung Injury with Prophylaxis and Mitigation of Damage from Radionuclides and Metals
Role: Co-Investigator
Funding: NORTHWESTERN UNIV via US ARMY MED RES ACQUISITION

Education

Postdoctoral Fellowships
1991 · Rockefeller University
PhD (Biological Sciences)
1985 · Stanford University
BS (Chemistry & Biology)
1979 · Jacksonville University

Contact Details

Phones:
Business:
(352) 273-6868
Emails:
Business:
johnaris@ufl.edu
Addresses:
Business Mailing:
PO Box 100235
1333 CENTER DR
GAINESVILLE FL 32610
Business Street:
1395 CENTER DR RM D2 32A
GAINESVILLE FL 32610