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UF Health University of Florida
Department of Molecular Genetics & Microbiology College of Medicine
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Sumita Bhaduri-McIntosh

Sumita Bhaduri-McIntosh, M.D., Ph.D.

Professor, Pediatric Infectious Diseases

Department: MD-PEDS-INFECTIOUS DISEASES
Business Phone: (352) 294-8591
Business Email: sbhaduri@peds.ufl.edu

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About Sumita Bhaduri-McIntosh

Related Links:
Bhaduri and McIntosh Laboratories
Additional Positions:
Editor-in-Chief
2024 – Current · PLOS Pathogens

Teaching Profile

Courses Taught

  1. PHY6910 – Supervised Research

    College of Liberal Arts and Sciences

  2. PHY7980 – Research for Doctoral Dissertation

    College of Liberal Arts and Sciences

  3. PHY6905 – Individual Work

    College of Liberal Arts and Sciences

  4. PHY7979 – Advanced Research

    College of Liberal Arts and Sciences

Board Certifications

  • Pediatric Infectious Diseases
    American Board of Pediatrics

Clinical Profile

Infectious Diseases, Immunodeficiency-associated cancers (transplant-related, HIV-related), Viral cancers, Infectious Mononucleosis

Specialties

  • Pediatric Infectious Disease

Areas of Interest

  • Congenital Cytomegalovirus
  • Congenital Syphilis
  • Congenital Toxoplasmosis
  • Ear Infection – Chronic
  • HIV/AIDS
  • Herpes – Oral
  • Nontuberculous Mycobacteria
  • Swollen Lymph Nodes
  • Traveling with Children

Research Profile

We study Epstein-Barr virus (EBV), the first human cancer-causing virus to be discovered. EBV causes infectious mononucleosis and is causal or linked to several B lymphocyte- and epithelial cell-cancers. Some of our experiments are designed to explore how EBV disturbs and exploits cellular physiology to drive unscheduled cell proliferation, a central feature of cancer. Other experiments are directed at understanding how this virus persists successfully in over 95% of humans. Both lines of investigation have revealed several targets for anti-cancer and anti-viral intervention.

Open Researcher and Contributor ID (ORCID)

0000-0003-2946-9497

Publications

Academic Articles

Grants

  1. Understanding viral mechanisms to inform oncolytic therapies for EBV-associated lymphomas in PLWH

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIDCR

  2. Exposing synthetic lethal vulnerabilities in EBV-positive AIDS-NHL through novel replication dependency factors

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIDCR

  3. Lytic Induction Project

    Role:
    Principal Investigator
    Funding:
    VIRACTA THERAPEUTICS

  4. Synthetic lethal targeting of EBV-positive diffuse large B cell lymphomas in persons living with HIV

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NCI

  5. Studying the capacity of the EBV protein kinase (BGLF4) plus ganciclovir vs acyclovir to induce cell killing in non-EBV infected A549 cells.

    Role:
    Principal Investigator
    Funding:
    VIRACTA THERAPEUTICS

  6. Studying the capacity of the EBV protein kinase (BGLF4) plus ganciclovir to induce cell killing in non-EBV infected 293 cells.

    Role:
    Principal Investigator
    Funding:
    VIRACTA THERAPEUTICS

  7. Nanotinostat and ganciclovir in an oncolytic strategy against EBV-lymphomas

    Role:
    Principal Investigator
    Funding:
    VIRACTA THERAPEUTICS

  8. Epstein-Barr virus and B-cell co-opted functions of the endogenous retrovirus envelope protein, Syncytin-1

    Role:
    Other
    Funding:
    NATL INST OF HLTH NIDCR

  9. Host determinants of Epstein-Barr virus lytic cycle activation

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NIAID

Contact Details

Phones:
Business:
(352) 294-8591
Emails:
Business:
sbhaduri@peds.ufl.edu
Addresses:
Business Mailing:
PO Box 100296
 GAINESVILLE FL 32610
Business Street:
1600 SW ARCHER RD
 GAINESVILLE FL 32610