Brian D Harfe,
Associate Dean/Assistant Provost
About Brian D Harfe
Fun Fact: My wife Kate and I paid for our wedding by performing dance gigs around the Atlanta area. The goal of our research is to elucidate how the limb and intervertebral discs form. Vertebrate digits form from mesenchymal cells that undergo differentiation through an invariant genetic program to form bone and cartilage elements, however, the molecular factors involved in establishing the invariant digit pattern are not well understood. A second focus is on age-related changes in intervertebral disks. Presently, there is no cure for disk degeneration, which is one cause of back pain. Our lab has investigated the molecular signaling pathways required for disk formation using the mouse model system. Currently, I serve as Associate Dean in the College of Liberal Arts and Sciences and as Interim Associate Provost.
Related Links:
Teaching Profile
Courses Taught
2013-2014,2016-2024
GMS6001 Fundamentals of Biomedical Sciences I
2010-2020
BMS6003 Genetics and Health
2016-2019
ZOO3603C Evolutionary Developmental Biology
2006,2008-2010,2010-2019,2012-2023,2019-2024,2021-2024,2023-2024
GMS6013 Developmental Genetics
2018
ZOO7980 Research for Doctoral Dissertation
2015
BMS4905 Medical Sciences Senior Research
2013-2014
PCB5065 Advanced Genetics
2014
BSC2009 Biological Sciences
2008,2010-2012,2012
GMS6151 Genetic Analysis Using Model Systems
2012
GMS6290 Genetics/Genomics Program Graduate Seminar
2010
IDH4917 Undergrad Research
2009
BMS6300C Med Micrbio/Infec Dis
2007
GMS6011 Mouse Genetics
2006
GMS6181 Spec Topics Microbiol
2023-2024
IDS2935 Special Topics
2024
IDS4956 Overseas Studies
2024
IDS4911 Undergraduate Research in Interdisciplinary Studies
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-4410-3525
Publications
2022
Intervertebral disc repair and regeneration: Insights from the notochord.
Seminars in cell & developmental biology.
127:3-9
[DOI] 10.1016/j.semcdb.2021.11.012.
[PMID] 34865989.
2022
Loss of BMP2 and BMP4 Signaling in the Dental Epithelium Causes Defective Enamel Maturation and Aberrant Development of Ameloblasts.
International journal of molecular sciences.
23(11)
[DOI] 10.3390/ijms23116095.
[PMID] 35682776.
2022
Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice.
Developmental cell.
57(17):2048-2062.e4
[DOI] 10.1016/j.devcel.2022.07.016.
[PMID] 35977544.
2019
Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development.
International journal of molecular sciences.
20(9)
[DOI] 10.3390/ijms20092275.
[PMID] 31072004.
2019
TMEM16A calcium-activated chloride currents in supporting cells of the mouse olfactory epithelium.
The Journal of general physiology.
151(7):954-966
[DOI] 10.1085/jgp.201812310.
[PMID] 31048412.
2017
Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.
PLoS genetics.
13(7)
[DOI] 10.1371/journal.pgen.1006914.
[PMID] 28715412.
2017
Developmental mechanisms of intervertebral disc and vertebral column formation.
Wiley interdisciplinary reviews. Developmental biology.
6(6)
[DOI] 10.1002/wdev.283.
[PMID] 28719048.
2017
SHH Protein Variance in the Limb Bud Is Constrained by Feedback Regulation and Correlates with Altered Digit Patterning.
G3 (Bethesda, Md.).
7(3):851-858
[DOI] 10.1534/g3.116.033019.
[PMID] 28131983.
2017
Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-10692-5.
[PMID] 28874804.
2016
BMPs are direct triggers of interdigital programmed cell death.
Developmental biology.
411(2):266-276
[DOI] 10.1016/j.ydbio.2015.12.016.
[PMID] 26826495.
2015
Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice.
PloS one.
10(6)
[DOI] 10.1371/journal.pone.0129171.
[PMID] 26067252.
2015
Musculoskeletal integration at the wrist underlies the modular development of limb tendons.
Development (Cambridge, England).
142(14):2431-41
[DOI] 10.1242/dev.122374.
[PMID] 26062940.
2015
Notochord to Nucleus Pulposus Transition.
Current osteoporosis reports.
13(5):336-41
[DOI] 10.1007/s11914-015-0284-x.
[PMID] 26231139.
2014
Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal.
The Journal of physiology.
592(18):4051-68
[DOI] 10.1113/jphysiol.2014.277152.
[PMID] 25063822.
2014
Dynamics of BMP signaling in limb bud mesenchyme and polydactyly.
Developmental biology.
393(2):270-281
[DOI] 10.1016/j.ydbio.2014.07.003.
[PMID] 25034710.
2014
Loss of Tmem16a Function Causes Vascular Abnormalities in Mice
Acta Physiologica.
211(696, SI)
2014
Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish.
Genesis (New York, N.Y. : 2000).
52(6):636-55
[DOI] 10.1002/dvg.22785.
[PMID] 24753112.
2013
An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool.
PLoS genetics.
9(12)
[DOI] 10.1371/journal.pgen.1003973.
[PMID] 24348261.
2013
Foxa1 and Foxa2 are required for formation of the intervertebral discs.
PloS one.
8(1)
[DOI] 10.1371/journal.pone.0055528.
[PMID] 23383217.
2013
Needle puncture injury causes acute and long-term mechanical deficiency in a mouse model of intervertebral disc degeneration.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
31(8):1276-82
[DOI] 10.1002/jor.22355.
[PMID] 23553925.
2013
Phylogenetic, expression, and functional analyses of anoctamin homologs in Caenorhabditis elegans.
American journal of physiology. Regulatory, integrative and comparative physiology.
305(11):R1376-89
[DOI] 10.1152/ajpregu.00303.2012.
[PMID] 24049119.
2013
The transmembrane protein 16A Ca(2+)-activated Cl- channel in airway smooth muscle contributes to airway hyperresponsiveness.
American journal of respiratory and critical care medicine.
187(4):374-81
[DOI] 10.1164/rccm.201207-1303OC.
[PMID] 23239156.
2012
A Transcription Factor-Microrna Autoregulatory Loop Determines Dopamine Neuron Numbers
International Journal of Developmental Neuroscience.
30(8):679-679
[DOI] 10.1016/j.ijdevneu.2012.10.027.
2012
Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.
Genes & development.
26(18):2088-102
[DOI] 10.1101/gad.187385.112.
[PMID] 22987639.
2012
Avian intervertebral disc arises from rostral sclerotome and lacks a nucleus pulposus: implications for evolution of the vertebrate disc.
Developmental dynamics : an official publication of the American Association of Anatomists.
241(4):675-83
[DOI] 10.1002/dvdy.23750.
[PMID] 22354863.
2012
Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth.
PloS one.
7(5)
[DOI] 10.1371/journal.pone.0037826.
[PMID] 22662233.
2012
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons.
Neuron.
74(1):179-92
[DOI] 10.1016/j.neuron.2012.01.033.
[PMID] 22500639.
2012
Electrical slow waves in the mouse oviduct are dependent upon a calcium activated chloride conductance encoded by Tmem16a.
Biology of reproduction.
86(1):1-7
[DOI] 10.1095/biolreprod.111.095554.
[PMID] 21976594.
2012
Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.
PLoS genetics.
8(7)
[DOI] 10.1371/journal.pgen.1002823.
[PMID] 22844247.
2012
Sonic hedgehog in the notochord is sufficient for patterning of the intervertebral discs.
Mechanisms of development.
129(9-12):255-62
[DOI] 10.1016/j.mod.2012.07.003.
[PMID] 22841806.
2012
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.
Nature neuroscience.
15(7):1015-21
[DOI] 10.1038/nn.3111.
[PMID] 22634729.
2012
Tmem16a and Nherf1 Regulate Ca2+and Camp Stimulated Cl- Secretion in Murine Colon
The FASEB's Journal.
26
2012
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression.
Cancer research.
72(13):3270-81
[DOI] 10.1158/0008-5472.CAN-12-0475-T.
[PMID] 22564524.
2011
Ano1 as a regulator of proliferation.
American journal of physiology. Gastrointestinal and liver physiology.
301(6):G1044-51
[DOI] 10.1152/ajpgi.00196.2011.
[PMID] 21940901.
2011
Degeneration and regeneration of the intervertebral disc: lessons from development.
Disease models & mechanisms.
4(1):31-41
[DOI] 10.1242/dmm.006403.
[PMID] 21123625.
2011
Hedgehog Signaling Is Required for Formation of the Notochord Sheath and Patterning of Nuclei Pulposi Within the Intervertebral Discs
Developmental Biology.
356(1)
[DOI] 10.1016/j.ydbio.2011.05.593.
2011
Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs.
Proceedings of the National Academy of Sciences of the United States of America.
108(23):9484-9
[DOI] 10.1073/pnas.1007566108.
[PMID] 21606373.
2011
Keeping up with the zone of polarizing activity: New roles for an old signaling center.
Developmental dynamics : an official publication of the American Association of Anatomists.
240(5):915-9
[DOI] 10.1002/dvdy.22597.
[PMID] 21360795.
2011
Micrornas in Dopamine Progenitor Specification
Developmental Biology.
356(1)
[DOI] 10.1016/j.ydbio.2011.05.208.
2011
Nuclei pulposi formation from the embryonic notochord occurs normally in GDF-5-deficient mice.
Spine.
36(24):E1555-61
[DOI] 10.1097/BRS.0b013e318210eec4.
[PMID] 21278629.
2011
The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning.
Developmental biology.
351(2):254-65
[DOI] 10.1016/j.ydbio.2011.01.005.
[PMID] 21256124.
2010
Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning.
Proceedings of the National Academy of Sciences of the United States of America.
107(12):5489-94
[DOI] 10.1073/pnas.0912818107.
[PMID] 20212115.
2010
The microRNA-processing enzyme dicer maintains juxtaglomerular cells.
Journal of the American Society of Nephrology : JASN.
21(3):460-7
[DOI] 10.1681/ASN.2009090964.
[PMID] 20056748.
2010
The sonic hedgehog pathway in chordoid tumours.
Histopathology.
56(7):978-9
[DOI] 10.1111/j.1365-2559.2010.03572.x.
[PMID] 20500228.
2010
Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells.
The Journal of biological chemistry.
285(17):12990-3001
[DOI] 10.1074/jbc.M109.068544.
[PMID] 20177062.
2009
Aberrant FGF signaling, independent of ectopic hedgehog signaling, initiates preaxial polydactyly in Dorking chickens.
Developmental biology.
334(1):133-41
[DOI] 10.1016/j.ydbio.2009.07.009.
[PMID] 19616534.
2009
Cell Lineage Analysis Demonstrates An Endodermal Origin of the Distal Urethra and Perineum Comment
Journal of Urology.
181
2009
Cell-Autonomous Role of Hedgehog Signaling in Notochord and Intervertebral Disc Development
Developmental Biology.
331(2)
[DOI] 10.1016/j.ydbio.2009.05.425.
2009
Cilia-Dependent Ventricular Targeting of Multimeric Shh in the Developing Neural Tube
Developmental Biology.
331(2)
[DOI] 10.1016/j.ydbio.2009.05.142.
2009
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles.
The Journal of physiology.
587(Pt 20):4887-904
[DOI] 10.1113/jphysiol.2009.176198.
[PMID] 19687122.
2009
Expression patterns of the Tmem16 gene family during cephalic development in the mouse.
Gene expression patterns : GEP.
9(3):178-91
[DOI] 10.1016/j.gep.2008.11.002.
[PMID] 19059364.
2009
Foxa Transcription Factors and the Intervertebral Disk
Developmental Biology.
331(2):501-529
[DOI] 10.1016/j.ydbio.2009.05.529.
2009
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.
Mammalian genome : official journal of the International Mammalian Genome Society.
20(3):140-51
[DOI] 10.1007/s00335-008-9169-y.
[PMID] 19169742.
2009
In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth.
Developmental biology.
327(2):516-23
[DOI] 10.1016/j.ydbio.2009.01.004.
[PMID] 19210962.
2009
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport.
The Journal of biological chemistry.
284(42):28698-703
[DOI] 10.1074/jbc.M109.012120.
[PMID] 19679661.
2009
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
23(9):2898-908
[DOI] 10.1096/fj.09-131342.
[PMID] 19423639.
2009
Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development.
Development (Cambridge, England).
136(23):3949-57
[DOI] 10.1242/dev.042291.
[PMID] 19906862.
2009
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice.
Developmental biology.
328(2):328-41
[DOI] 10.1016/j.ydbio.2009.01.037.
[PMID] 19389351.
2009
Sertoli cell Dicer is essential for spermatogenesis in mice.
Developmental biology.
326(1):250-9
[DOI] 10.1016/j.ydbio.2008.11.011.
[PMID] 19071104.
2009
Studies on expression and function of the TMEM16A calcium-activated chloride channel.
Proceedings of the National Academy of Sciences of the United States of America.
106(50):21413-8
[DOI] 10.1073/pnas.0911935106.
[PMID] 19965375.
2009
The Microrna Processing Enzymediceris Required for Maintenance of the Renin Cell Phenotype in Vivo
Hypertension.
54
2009
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A.
The Journal of biological chemistry.
284(42):28571-8
[DOI] 10.1074/jbc.M109.010074.
[PMID] 19654323.
2009
Tmem16a Is a Ca++ Regulated Co-Secretory Channel in Mouse Airways
Pediatric Pulmonology.
2009
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways.
The Journal of biological chemistry.
284(22):14875-80
[DOI] 10.1074/jbc.C109.000869.
[PMID] 19363029.
2008
BMP4 is dispensable for skeletogenesis and fracture-healing in the limb.
The Journal of bone and joint surgery. American volume.
90 Suppl 1:14-8
[DOI] 10.2106/JBJS.G.01109.
[PMID] 18292351.
2008
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum.
Developmental biology.
318(1):143-52
[DOI] 10.1016/j.ydbio.2008.03.017.
[PMID] 18439576.
2008
Characterization of Tmem16F in Vertebrate Development
Developmental Biology.
319(2):508-509
[DOI] 10.1016/j.ydbio.2008.05.149.
2008
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
28(17):4322-30
[DOI] 10.1523/JNEUROSCI.4815-07.2008.
[PMID] 18434510.
2008
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
28(19):4878-87
[DOI] 10.1523/JNEUROSCI.0828-08.2008.
[PMID] 18463241.
2008
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America.
105(14):5614-9
[DOI] 10.1073/pnas.0801689105.
[PMID] 18385371.
2008
Dicer1 is required for differentiation of the mouse male germline.
Biology of reproduction.
79(4):696-703
[DOI] 10.1095/biolreprod.108.067827.
[PMID] 18633141.
2008
Expression of TMEM16 paralogs during murine embryogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists.
237(9):2566-74
[DOI] 10.1002/dvdy.21676.
[PMID] 18729231.
2008
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation.
Developmental dynamics : an official publication of the American Association of Anatomists.
237(12):3953-8
[DOI] 10.1002/dvdy.21805.
[PMID] 19035356.
2008
Members of the miRNA-200 family regulate olfactory neurogenesis.
Neuron.
57(1):41-55
[DOI] 10.1016/j.neuron.2007.11.018.
[PMID] 18184563.
2008
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease.
Journal of the American Society of Nephrology : JASN.
19(11):2150-8
[DOI] 10.1681/ASN.2008020233.
[PMID] 18776121.
2008
Sonic Hedgehog Signaling in the Apical Ectodermal Ridge Is Essential for Proper Patterning of the Vertebrate Limb
Developmental Biology.
319(2):597-598
[DOI] 10.1016/j.ydbio.2008.05.517.
2008
The transmembrane protein TMEM16A is required for normal development of the murine trachea.
Developmental biology.
321(1):141-9
[DOI] 10.1016/j.ydbio.2008.06.009.
[PMID] 18585372.
2007
Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling.
Developmental cell.
12(1):99-112
[PMID] 17199044.
2007
Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb.
Developmental biology.
304(1):9-21
[PMID] 17300775.
2007
Epidermal stem cells arise from the hair follicle after wounding.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
21(7):1358-66
[PMID] 17255473.
2007
Essential role for Dicer during skeletal muscle development.
Developmental biology.
311(2):359-68
[PMID] 17936265.
2007
Identification of genes expressed in the mouse limb using a novel ZPA microarray approach.
Gene expression patterns : GEP.
8(1):19-26
[PMID] 17911046.
2007
MicroRNA expression is required for pancreatic islet cell genesis in the mouse.
Diabetes.
56(12):2938-45
[PMID] 17804764.
2006
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing.
Nature genetics.
38(12):1424-9
[PMID] 17099713.
2006
Dicer function is essential for lung epithelium morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America.
103(7):2208-13
[PMID] 16452165.
2006
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis.
PLoS genetics.
2(12)
[PMID] 17194222.
2006
MicroRNAs in development.
TheScientificWorldJournal.
6:1828-40
[PMID] 17205190.
2006
MicroRNAs in mammalian development and tumorigenesis.
Birth defects research. Part C, Embryo today : reviews.
78(2):172-9
[PMID] 16847882.
2005
Analysis of the regulation of lin-41 during chick and mouse limb development.
Developmental dynamics : an official publication of the American Association of Anatomists.
234(4):948-60
[PMID] 16245339.
2005
Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning.
Development (Cambridge, England).
132(19):4235-45
[PMID] 16120640.
2005
Distinct stem cell populations regenerate the follicle and interfollicular epidermis.
Developmental cell.
9(6):855-61
[PMID] 16326396.
2005
Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation.
Developmental biology.
285(2):490-5
[PMID] 16109396.
2005
MicroRNAs in vertebrate development.
Current opinion in genetics & development.
15(4):410-5
[PMID] 15979303.
2005
Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand.
Development (Cambridge, England).
132(1):133-42
[PMID] 15576405.
2005
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development.
Nature.
438(7068):671-4
[PMID] 16319892.
2005
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb.
Proceedings of the National Academy of Sciences of the United States of America.
102(31):10898-903
[PMID] 16040801.
2004
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.
Cell.
118(4):517-28
[PMID] 15315763.
2004
Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
18(15):1834-50
[PMID] 15576487.
2004
MicroRNA-responsive ‘sensor’ transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression.
Nature genetics.
36(10):1079-83
[PMID] 15361871.
2004
The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells.
Science (New York, N.Y.).
305(5682):396-9
[PMID] 15256670.
2003
A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.
Developmental cell.
5(6):937-44
[PMID] 14667415.
2003
Wnt signalling regulates myogenic differentiation in the developing avian wing.
Development (Cambridge, England).
130(15):3503-14
[PMID] 12810597.
2002
16 Wnt regulation of limb muscle differentiation.
Journal of anatomy.
201(5)
[PMID] 17103759.
2002
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae.
Molecular and cellular biology.
22(24):8756-62
[PMID] 12446792.
2000
Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast.
Current biology : CB.
10(3):145-8
[PMID] 10679328.
2000
DNA mismatch repair and genetic instability.
Annual review of genetics.
34:359-399
[PMID] 11092832.
2000
DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae.
Molecular cell.
6(6):1491-9
[PMID] 11163221.
2000
dpy-18 encodes an alpha-subunit of prolyl-4-hydroxylase in caenorhabditis elegans.
Genetics.
155(3):1139-48
[PMID] 10880476.
2000
Mismatch repair proteins and mitotic genome stability.
Mutation research.
451(1-2):151-67
[PMID] 10915870.
2000
Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.
Genetics.
156(2):571-8
[PMID] 11014807.
1999
Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae.
Molecular and cellular biology.
19(7):4766-73
[PMID] 10373526.
1998
Analysis of a Caenorhabditis elegans Twist homolog identifies conserved and divergent aspects of mesodermal patterning.
Genes & development.
12(16):2623-35
[PMID] 9716413.
1998
Muscle and nerve-specific regulation of a novel NK-2 class homeodomain factor in Caenorhabditis elegans.
Development (Cambridge, England).
125(3):421-9
[PMID] 9425137.
1998
MyoD and the specification of muscle and non-muscle fates during postembryonic development of the C. elegans mesoderm.
Development (Cambridge, England).
125(13):2479-88
[PMID] 9609831.
1997
A C. elegans E/Daughterless bHLH protein marks neuronal but not striated muscle development.
Development (Cambridge, England).
124(11):2179-89
[PMID] 9187144.
1995
Molecular dissection of the epsilon subunit of the chloroplast ATP synthase of spinach.
Plant physiology.
109(4):1379-88
[PMID] 8539297.
1993
Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cells.
Journal of virology.
67(9):5198-205
[PMID] 8350395.
Grants
Jul 2017
– May 2019
Regenerative potential of embryonic notochordal nucleus pulposus progenitors
Role: Principal Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH NIAMS
Contact Details
Phones:
- Business:
- (352) 294-1955
Emails:
- Business:
- bharfe@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 117300
GAINESVILLE FL 32611 - Business Street:
-
TURLINGTON HALL 2014
GAINESVILLE FL 326100001