Mark Q Martindale

Mark Q Martindale,

Director And Professor

Department: WH-ADMINISTRATION
Business Phone: (904) 201-8452
Business Email: mqmartin@whitney.ufl.edu

Teaching Profile

Courses Taught
2018
FAS7980 Research for Doctoral Dissertation
2018
GMS7980 Research for Doctoral Dissertation
2018
ZOO7980 Research for Doctoral Dissertation

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-5805-5640

Publications

2022
A novel regulatory gene promotes novel cell fate by suppressing ancestral fate in the sea anemone Nematostella vectensis
Proceedings of the National Academy of Sciences. 119(19) [DOI] 10.1073/pnas.2113701119. [PMID] 35500123.
2022
Assessment of Optimal Conditions for Marine Invertebrate Cell-Mediated Mineralization of Organic Matrices
Biomimetics. 7(3) [DOI] 10.3390/biomimetics7030086. [PMID] 35892356.
2022
Cnidarian-Symbiodiniaceae symbiosis establishment is independent of photosynthesis.
Current biology : CB. 32(11):2402-2415.e4 [DOI] 10.1016/j.cub.2022.04.021. [PMID] 35504283.
2022
Ctenophores are direct developers that reproduce continuously beginning very early after hatching
Proceedings of the National Academy of Sciences. 119(18) [DOI] 10.1073/pnas.2122052119. [PMID] 35476523.
2022
Emerging models: The “development” of the ctenophore Mnemiopsis leidyi and the cnidarian Nematostella vectensis as useful experimental models.
Current topics in developmental biology. 147:93-120 [DOI] 10.1016/bs.ctdb.2022.02.002. [PMID] 35337468.
2022
Studying Ctenophora WBR Using Mnemiopsis leidyi
Methods in Molecular Biology. 95-119 [DOI] 10.1007/978-1-0716-2172-1_5.
2021
Improved histological fixation of gelatinous marine invertebrates
Frontiers in Zoology. 18(1) [DOI] 10.1186/s12983-021-00414-z. [PMID] 34118945.
2021
Whole-Body Regeneration in the Lobate Ctenophore Mnemiopsis leidyi
Genes. 12(6) [DOI] 10.3390/genes12060867. [PMID] 34198839.
2020
Adaptation to Bleaching: Are Thermotolerant Symbiodiniaceae Strains More Successful Than Other Strains Under Elevated Temperatures in a Model Symbiotic Cnidarian?
Frontiers in microbiology. 11 [DOI] 10.3389/fmicb.2020.00822. [PMID] 32431680.
2020
Genes with spiralian-specific protein motifs are expressed in spiralian ciliary bands
Nature Communications. 11(1) [DOI] 10.1038/s41467-020-17780-7. [PMID] 32820176.
2020
Par protein localization during the early development of Mnemiopsis leidyi suggests different modes of epithelial organization in the metazoa.
eLife. 9 [DOI] 10.7554/eLife.54927. [PMID] 32716297.
2019
“Dorsal-Ventral” Genes Are Part of an Ancient Axial Patterning System: Evidence from Trichoplax adhaerens (Placozoa).
Molecular biology and evolution. 36(5):966-973 [DOI] 10.1093/molbev/msz025. [PMID] 30726986.
2019
Author Correction: The mid-developmental transition and the evolution of animal body plans.
Nature. 575(7782) [DOI] 10.1038/s41586-019-1698-x. [PMID] 31673121.
2019
Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis.
National science review. 6(5):993-1003 [DOI] 10.1093/nsr/nwz064. [PMID] 34691960.
2019
Genomic analysis of the tryptome reveals molecular mechanisms of gland cell evolution.
EvoDevo. 10 [DOI] 10.1186/s13227-019-0138-1. [PMID] 31583070.
2019
Molecular patterning during the development of Phoronopsis harmeri reveals similarities to rhynchonelliform brachiopods
EvoDevo. 10(1) [DOI] 10.1186/s13227-019-0146-1. [PMID] 31867094.
2019
Perspectives on the expansion of human precision oncology and genomic approaches to sea turtle fibropapillomatosis
Communications Biology. 2(1) [DOI] 10.1038/s42003-019-0301-1. [PMID] 30775456.
2019
Regeneration in the ctenophore Mnemiopsis leidyi occurs in the absence of a blastema, requires cell division, and is temporally separable from wound healing
BMC Biology. 17(1) [DOI] 10.1186/s12915-019-0695-8. [PMID] 31604443.
2018
Acquisition and proliferation of algal symbionts in bleached polyps of the upside-down jellyfish, Cassiopea xamachana
Journal of Experimental Marine Biology and Ecology. 508:44-51 [DOI] 10.1016/j.jembe.2018.08.010.
2018
Author response: CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone
. [DOI] 10.7554/elife.39742.021.
2018
Author response: Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm
. [DOI] 10.7554/elife.36740.045.
2018
CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone
eLife. 7 [DOI] 10.7554/elife.39742.
2018
CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone
eLife. 7 [DOI] 10.7554/elife.39742.
2018
Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm
eLife. 7 [DOI] 10.7554/elife.36740.
2018
Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm
eLife. 7 [DOI] 10.7554/elife.36740.
2018
Hox and Wnt pattern the primary body axis of an anthozoan cnidarian before gastrulation
Nature Communications. 9(1) [DOI] 10.1038/s41467-018-04184-x. [PMID] 29789526.
2018
Integrating Embryonic Development and Evolutionary History to Characterize Tentacle-Specific Cell Types in a Ctenophore.
Molecular biology and evolution. 35(12):2940-2956 [DOI] 10.1093/molbev/msy171. [PMID] 30169705.
2018
Reengineering the primary body axis by ectopic cWnt signaling.
Current biology : CB. 28(5):R206-R207 [DOI] 10.1016/j.cub.2018.01.042. [PMID] 29510105.
2018
Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers
Communications Biology. 1(1) [DOI] 10.1038/s42003-018-0059-x. [PMID] 30271945.
2017
A bipolar role of the transcription factor ERG for cnidarian germ layer formation and apical domain patterning.
Developmental biology. 430(2):346-361 [DOI] 10.1016/j.ydbio.2017.08.015. [PMID] 28818668.
2017
Antagonistic BMP–cWNT signaling in the cnidarian Nematostella vectensis reveals insight into the evolution of mesoderm
Proceedings of the National Academy of Sciences. 114(28) [DOI] 10.1073/pnas.1701607114. [PMID] 28652368.
2017
Cas9-mediated excision ofNematostella brachyurydisrupts endoderm development, pharynx formation, and oral-aboral patterning
Development. [DOI] 10.1242/dev.145839. [PMID] 28705897.
2017
Food availability drives plastic self-repair response in a basal metazoan- case study on the ctenophore Mnemiopsis leidyi A. Agassiz 1865.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-16346-w. [PMID] 29180635.
2017
PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis.
EvoDevo. 8 [DOI] 10.1186/s13227-017-0077-7. [PMID] 28878874.
2017
Phylogenetic evidence for the modular evolution of metazoan signalling pathways
Philosophical Transactions of the Royal Society B: Biological Sciences. 372(1713) [DOI] 10.1098/rstb.2015.0477. [PMID] 27994120.
2017
Precision wildlife medicine: applications of the human-centred precision medicine revolution to species conservation.
Global change biology. 23(5):1792-1805 [DOI] 10.1111/gcb.13548. [PMID] 27809394.
2017
The maternal-zygotic transition and zygotic activation of the Mnemiopsis leidyi genome occurs within the first three cleavage cycles.
Molecular reproduction and development. 84(11):1218-1229 [DOI] 10.1002/mrd.22926. [PMID] 29068507.
2016
Developmental expression of “germline”- and “sex determination”-related genes in the ctenophore Mnemiopsis leidyi.
EvoDevo. 7 [DOI] 10.1186/s13227-016-0051-9. [PMID] 27489613.
2016
Do novel genes drive morphological novelty? An investigation of the nematosomes in the sea anemone Nematostella vectensis.
BMC evolutionary biology. 16(1) [DOI] 10.1186/s12862-016-0683-3. [PMID] 27216622.
2016
MAPK signaling is necessary for neurogenesis in Nematostella vectensis.
BMC biology. 14 [DOI] 10.1186/s12915-016-0282-1. [PMID] 27480076.
2016
The developmental basis for the recurrent evolution of deuterostomy and protostomy.
Nature ecology & evolution. 1(1) [DOI] 10.1038/s41559-016-0005. [PMID] 28812551.
2016
The mid-developmental transition and the evolution of animal body plans.
Nature. 531(7596):637-641 [DOI] 10.1038/nature16994. [PMID] 26886793.
2016
The onset of regenerative properties in ctenophores.
Current opinion in genetics & development. 40:113-119 [DOI] 10.1016/j.gde.2016.06.017. [PMID] 27420173.
2015
Analysis of a spatial gene expression database for sea anemone Nematostella vectensis during early development.
BMC systems biology. 9 [DOI] 10.1186/s12918-015-0209-4. [PMID] 26400098.
2015
Current directions and future perspectives from the third Nematostella research conference.
Zoology (Jena, Germany). 118(2):135-40 [DOI] 10.1016/j.zool.2014.06.005. [PMID] 25450665.
2015
Ether-à-go-go family voltage-gated K+ channels evolved in an ancestral metazoan and functionally diversified in a cnidarian-bilaterian ancestor.
The Journal of experimental biology. 218(Pt 4):526-36 [DOI] 10.1242/jeb.110080. [PMID] 25696816.
2015
Inputs of Bmp Signaling in To the Cnidarian Endomesoderm Grn
Integrative and Comparative Biology. 55(1)
2015
Major diversification of voltage-gated K+ channels occurred in ancestral parahoxozoans.
Proceedings of the National Academy of Sciences of the United States of America. 112(9):E1010-9 [DOI] 10.1073/pnas.1422941112. [PMID] 25691740.
2015
Mesodermal gene expression during the embryonic and larval development of the articulate brachiopod Terebratalia transversa.
EvoDevo. 6 [DOI] 10.1186/s13227-015-0004-8. [PMID] 25897375.
2015
Nodal signaling is required for mesodermal and ventral but not for dorsal fates in the indirect developing hemichordate, Ptychodera flava.
Biology open. 4(7):830-42 [DOI] 10.1242/bio.011809. [PMID] 25979707.
2015
Par system components are asymmetrically localized in ectodermal epithelia, but not during early development in the sea anemone Nematostella vectensis.
EvoDevo. 6 [DOI] 10.1186/s13227-015-0014-6. [PMID] 26101582.
2015
Piecing Together the Cnidocyte Gene Regulatory Network
Integrative and Comparative Biology. 55(1)
2014
A cleavage clock regulates features of lineage-specific differentiation in the development of a basal branching metazoan, the ctenophore Mnemiopsis leidyi.
EvoDevo. 5(1) [DOI] 10.1186/2041-9139-5-4. [PMID] 24485336.
2014
A computational approach towards a gene regulatory network for the developing Nematostella vectensis gut.
PloS one. 9(7) [DOI] 10.1371/journal.pone.0103341. [PMID] 25076223.
2014
Aryl hydrocarbon receptor (AHR) in the cnidarian Nematostella vectensis: comparative expression, protein interactions, and ligand binding.
Development genes and evolution. 224(1):13-24 [DOI] 10.1007/s00427-013-0458-4. [PMID] 24292160.
2014
Developmental and light-entrained expression of melatonin and its relationship to the circadian clock in the sea anemone Nematostella vectensis.
EvoDevo. 5 [DOI] 10.1186/2041-9139-5-26. [PMID] 25243057.
2014
Expression of multiple Sox genes through embryonic development in the ctenophore Mnemiopsis leidyi is spatially restricted to zones of cell proliferation.
EvoDevo. 5 [DOI] 10.1186/2041-9139-5-15. [PMID] 24834317.
2014
Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr.
Proceedings of the National Academy of Sciences of the United States of America. 111(15):5712-7 [DOI] 10.1073/pnas.1321716111. [PMID] 24706772.
2014
In vivo imaging of Nematostella vectensis embryogenesis and late development using fluorescent probes.
BMC cell biology. 15 [DOI] 10.1186/s12860-014-0044-2. [PMID] 25433655.
2014
Initiating a regenerative response; cellular and molecular features of wound healing in the cnidarian Nematostella vectensis.
BMC biology. 12 [DOI] 10.1186/1741-7007-12-24. [PMID] 24670243.
2014
Non-canonical Notch signaling represents an ancestral mechanism to regulate neural differentiation.
EvoDevo. 5 [DOI] 10.1186/2041-9139-5-30. [PMID] 25705370.
2014
Notch Signaling May Have Evolved To Control Cellular Differentiation and Growth During Development of Metazoan Animals
Integrative and Comparative Biology. 54(1)
2014
Old cell, new trick? Cnidocytes as a model for the evolution of novelty.
Integrative and comparative biology. 54(4):714-22 [DOI] 10.1093/icb/icu027. [PMID] 24771087.
2014
The cell’s view of animal body-plan evolution.
Integrative and comparative biology. 54(4):658-66 [DOI] 10.1093/icb/icu108. [PMID] 25108284.
2014
The Global Invertebrate Genomics Alliance (GIGA): developing community resources to study diverse invertebrate genomes.
The Journal of heredity. 105(1):1-18 [DOI] 10.1093/jhered/est084. [PMID] 24336862.
2014
Understanding Animal Polarity: Functional Studies During Early Embryogenesis of the Sea Anemone Nematostella Vectensis.
Integrative and Comparative Biology. 54(1)
2013
Characterizing the spatiotemporal expression of RNAs and proteins in the starlet sea anemone, Nematostella vectensis.
Nature protocols. 8(5):900-15 [DOI] 10.1038/nprot.2013.014. [PMID] 23579779.
2013
Ectopic activation of the canonical wnt signaling pathway affects ectodermal patterning along the primary axis during larval development in the anthozoan Nematostella vectensis.
Developmental biology. 380(2):324-34 [DOI] 10.1016/j.ydbio.2013.05.022. [PMID] 23722001.
2013
Evidence for a phototransduction cascade in an early brachiopod embryo.
Integrative and comparative biology. 53(1):17-26 [DOI] 10.1093/icb/ict037. [PMID] 23630970.
2013
Going where traditional markers have not gone before: utility of and promise for RAD sequencing in marine invertebrate phylogeography and population genomics.
Molecular ecology. 22(11):2953-70 [DOI] 10.1111/mec.12228. [PMID] 23473066.
2013
Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis.
Nature protocols. 8(5):924-34 [DOI] 10.1038/nprot.2013.009. [PMID] 23579781.
2013
The genome of the ctenophore Mnemiopsis leidyi and its implications for cell type evolution.
Science (New York, N.Y.). 342(6164) [DOI] 10.1126/science.1242592. [PMID] 24337300.
2012
A framework for the establishment of a cnidarian gene regulatory network for “endomesoderm” specification: the inputs of ß-catenin/TCF signaling.
PLoS genetics. 8(12) [DOI] 10.1371/journal.pgen.1003164. [PMID] 23300467.
2012
Activation of Pax7-positive cells in a non-contractile tissue contributes to regeneration of myogenic tissues in the electric fish S. macrurus.
PloS one. 7(5) [DOI] 10.1371/journal.pone.0036819. [PMID] 22685526.
2012
Cell proliferation is necessary for the regeneration of oral structures in the anthozoan cnidarian Nematostella vectensis.
BMC developmental biology. 12 [DOI] 10.1186/1471-213X-12-34. [PMID] 23206430.
2012
Cephalopod genomics: A plan of strategies and organization.
Standards in genomic sciences. 7(1):175-88 [DOI] 10.4056/sigs.3136559. [PMID] 23451296.
2012
Coral comparative genomics reveal expanded Hox cluster in the cnidarian-bilaterian ancestor.
Integrative and comparative biology. 52(6):835-41 [DOI] 10.1093/icb/ics098. [PMID] 22767488.
2012
Development of the larval anterior neurogenic domains of Terebratalia transversa (Brachiopoda) provides insights into the diversification of larval apical organs and the spiralian nervous system.
EvoDevo. 3 [DOI] 10.1186/2041-9139-3-3. [PMID] 22273002.
2012
Expanded functional diversity of shaker K(+) channels in cnidarians is driven by gene expansion.
PloS one. 7(12) [DOI] 10.1371/journal.pone.0051366. [PMID] 23251506.
2012
Functional roles of Notch signaling in the cnidarian Nematostella vectensis.
Developmental biology. 362(2):295-308 [DOI] 10.1016/j.ydbio.2011.11.012. [PMID] 22155407.
2012
Genomic organization, evolution, and expression of photoprotein and opsin genes in Mnemiopsis leidyi: a new view of ctenophore photocytes.
BMC biology. 10 [DOI] 10.1186/1741-7007-10-107. [PMID] 23259493.
2012
Lim homeobox genes in the Ctenophore Mnemiopsis leidyi: the evolution of neural cell type specification.
EvoDevo. 3(1) [DOI] 10.1186/2041-9139-3-2. [PMID] 22239757.
2012
Nematostella vectensis achaete-scute homolog NvashA regulates embryonic ectodermal neurogenesis and represents an ancient component of the metazoan neural specification pathway.
Development (Cambridge, England). 139(5):1013-22 [DOI] 10.1242/dev.073221. [PMID] 22318631.
2012
Specificity of associations between bacteria and the coral Pocillopora meandrina during early development.
Applied and environmental microbiology. 78(20):7467-75 [PMID] 22904048.
2011
A comparative gene expression database for invertebrates.
EvoDevo. 2 [DOI] 10.1186/2041-9139-2-17. [PMID] 21861937.
2011
Ciliary photoreceptors in the cerebral eyes of a protostome larva.
EvoDevo. 2 [DOI] 10.1186/2041-9139-2-6. [PMID] 21362157.
2011
Evolution of the TGF-β signaling pathway and its potential role in the ctenophore, Mnemiopsis leidyi.
PloS one. 6(9) [DOI] 10.1371/journal.pone.0024152. [PMID] 21931657.
2011
Extreme mitochondrial evolution in the ctenophore Mnemiopsis leidyi: Insight from mtDNA and the nuclear genome.
Mitochondrial DNA. 22(4):130-42 [DOI] 10.3109/19401736.2011.624611. [PMID] 21985407.
2011
Gene expression in bryozoan larvae suggest a fundamental importance of pre-patterned blastemic cells in the bryozoan life-cycle.
EvoDevo. 2(1) [DOI] 10.1186/2041-9139-2-13. [PMID] 21645327.
2011
Nuclear receptors from the ctenophore Mnemiopsis leidyi lack a zinc-finger DNA-binding domain: lineage-specific loss or ancestral condition in the emergence of the nuclear receptor superfamily?
EvoDevo. 2(1) [DOI] 10.1186/2041-9139-2-3. [PMID] 21291545.
2011
Ventralization of an indirect developing hemichordate by NiCl₂ suggests a conserved mechanism of dorso-ventral (D/V) patterning in Ambulacraria (hemichordates and echinoderms).
Developmental biology. 354(1):173-90 [DOI] 10.1016/j.ydbio.2011.03.030. [PMID] 21466800.
2010
A comprehensive fate map by intracellular injection of identified blastomeres in the marine polychaete Capitella teleta.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-8. [PMID] 20849573.
2010
A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia) in the Cnidaria and Protostomia.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-3. [PMID] 20849646.
2010
Developmental expression of COE across the Metazoa supports a conserved role in neuronal cell-type specification and mesodermal development.
Development genes and evolution. 220(7-8):221-34 [DOI] 10.1007/s00427-010-0343-3. [PMID] 21069538.
2010
Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-12. [PMID] 21054859.
2010
Genomic insights into Wnt signaling in an early diverging metazoan, the ctenophore Mnemiopsis leidyi.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-10. [PMID] 20920349.
2010
Highly conserved functions of the Brachyury gene on morphogenetic movements: insight from the early-diverging phylum Ctenophora.
Developmental biology. 339(1):212-22 [DOI] 10.1016/j.ydbio.2009.12.019. [PMID] 20036227.
2010
The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages.
BMC evolutionary biology. 10 [DOI] 10.1186/1471-2148-10-101. [PMID] 20398424.
2010
The homeodomain complement of the ctenophore Mnemiopsis leidyi suggests that Ctenophora and Porifera diverged prior to the ParaHoxozoa.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-9. [PMID] 20920347.
2010
Welcome to open access publishing at EvoDevo: a macroevolutionary change in sharing data.
EvoDevo. 1(1) [DOI] 10.1186/2041-9139-1-1. [PMID] 20849644.
2010
β-catenin and early development in the gastropod, Crepidula fornicata.
Integrative and comparative biology. 50(5):707-19 [DOI] 10.1093/icb/icq076. [PMID] 21558234.
2009
A developmental perspective: changes in the position of the blastopore during bilaterian evolution.
Developmental cell. 17(2):162-74 [DOI] 10.1016/j.devcel.2009.07.024. [PMID] 19686678.
2009
Anatomy and development of the nervous system of Nematostella vectensis, an anthozoan cnidarian.
Developmental neurobiology. 69(4):235-54 [DOI] 10.1002/dneu.20698. [PMID] 19170043.
2009
Assessing the root of bilaterian animals with scalable phylogenomic methods.
Proceedings. Biological sciences. 276(1677):4261-70 [DOI] 10.1098/rspb.2009.0896. [PMID] 19759036.
2009
Centralization of the deuterostome nervous system predates chordates.
Current biology : CB. 19(15):1264-9 [DOI] 10.1016/j.cub.2009.05.063. [PMID] 19559615.
2009
Coordinated spatial and temporal expression of Hox genes during embryogenesis in the acoel Convolutriloba longifissura.
BMC biology. 7 [DOI] 10.1186/1741-7007-7-65. [PMID] 19796382.
2009
The onset of microbial associations in the coral Pocillopora meandrina.
The ISME journal. 3(6):685-99 [DOI] 10.1038/ismej.2009.3. [PMID] 19242535.
2008
Acoel development indicates the independent evolution of the bilaterian mouth and anus.
Nature. 456(7220):382-6 [DOI] 10.1038/nature07309. [PMID] 18806777.
2008
Acoel development supports a simple planula-like urbilaterian.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 363(1496):1493-501 [DOI] 10.1098/rstb.2007.2239. [PMID] 18192185.
2008
Beta-catenin is required for the establishment of vegetal embryonic fates in the nemertean, Cerebratulus lacteus.
Developmental biology. 317(1):368-79 [DOI] 10.1016/j.ydbio.2008.02.042. [PMID] 18387602.
2008
Broad phylogenomic sampling improves resolution of the animal tree of life.
Nature. 452(7188):745-9 [DOI] 10.1038/nature06614. [PMID] 18322464.
2008
Cell-cell adhesion in the cnidaria: insights into the evolution of tissue morphogenesis.
The Biological bulletin. 214(3):218-32 [PMID] 18574100.
2008
Comb jellies (ctenophora): a model for Basal metazoan evolution and development.
CSH protocols. 2008 [DOI] 10.1101/pdb.emo106. [PMID] 21356709.
2008
Ctenophore tissue preparation and extraction of DNA.
CSH protocols. 2008 [DOI] 10.1101/pdb.prot5088. [PMID] 21356728.
2008
Ctenophore tissue preparation and extraction of RNA.
CSH protocols. 2008 [DOI] 10.1101/pdb.prot5089. [PMID] 21356729.
2008
Ctenophore whole-mount antibody staining.
CSH protocols. 2008 [DOI] 10.1101/pdb.prot5086. [PMID] 21356726.
2008
Ctenophore whole-mount in situ hybridization.
CSH protocols. 2008 [DOI] 10.1101/pdb.prot5087. [PMID] 21356727.
2008
Ctenophores.
Current biology : CB. 18(24):R1119-20 [DOI] 10.1016/j.cub.2008.10.004. [PMID] 19108762.
2008
Developmental expression of homeobox genes in the ctenophore Mnemiopsis leidyi.
Development genes and evolution. 218(6):307-19 [DOI] 10.1007/s00427-008-0222-3. [PMID] 18504608.
2008
Mnemiopsis leidyi Spawning and Embryo Collection.
CSH protocols. 2008 [DOI] 10.1101/pdb.prot5085. [PMID] 21356725.
2008
The Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolution.
Developmental biology. 313(2):501-18 [PMID] 18068698.
2007
Asymmetric developmental potential along the animal-vegetal axis in the anthozoan cnidarian, Nematostella vectensis, is mediated by Dishevelled.
Developmental biology. 310(1):169-86 [PMID] 17716645.
2007
Embryonic development in two species of scleractinian coral embryos: Symbiodinium localization and mode of gastrulation.
Evolution & development. 9(4):355-67 [PMID] 17651360.
2007
Expression of Pax gene family members in the anthozoan cnidarian, Nematostella vectensis.
Evolution & development. 9(1):25-38 [PMID] 17227364.
2007
FGF signaling in gastrulation and neural development in Nematostella vectensis, an anthozoan cnidarian.
Development genes and evolution. 217(2):137-48 [PMID] 17237944.
2007
Gastrulation in the cnidarian Nematostella vectensis occurs via invagination not ingression.
Developmental biology. 305(2):483-97 [PMID] 17397821.
2007
Genomic organization, gene structure, and developmental expression of three clustered otx genes in the sea anemone Nematostella vectensis.
Journal of experimental zoology. Part B, Molecular and developmental evolution. 308(4):494-506 [PMID] 17377951.
2007
High-resolution fate map of the snail Crepidula fornicata: the origins of ciliary bands, nervous system, and muscular elements.
Developmental biology. 305(1):63-76 [PMID] 17346693.
2007
Homology of ciliary bands in Spiralian Trochophores.
Integrative and comparative biology. 47(6):865-71 [DOI] 10.1093/icb/icm035. [PMID] 21669765.
2007
Phylogenetic analysis of lineage relationships among hyperiid amphipods as revealed by examination of the mitochondrial gene, cytochrome oxidase I (COI).
Integrative and comparative biology. 47(6):815-30 [DOI] 10.1093/icb/icm093. [PMID] 21669761.
2007
Pre-bilaterian origins of the Hox cluster and the Hox code: evidence from the sea anemone, Nematostella vectensis.
PloS one. 2(1) [PMID] 17252055.
2007
Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization.
Science (New York, N.Y.). 317(5834):86-94 [PMID] 17615350.
2007
Surprisingly complex T-box gene complement in diploblastic metazoans.
Evolution & development. 9(3):220-30 [PMID] 17501746.
2007
The evolutionary origin of hedgehog proteins.
Current biology : CB. 17(19):R836-7 [PMID] 17925209.
2007
The Hox gene complement of a pelagic chaetognath, Flaccisagitta enflata.
Integrative and comparative biology. 47(6):854-64 [DOI] 10.1093/icb/icm077. [PMID] 21669764.
2006
A WNT of things to come: evolution of Wnt signaling and polarity in cnidarians.
Seminars in cell & developmental biology. 17(2):157-67 [PMID] 16765608.
2006
Broad taxon and gene sampling indicate that chaetognaths are protostomes.
Current biology : CB. 16(15):R575-6 [PMID] 16890509.
2006
Cell specification and the role of the polar lobe in the gastropod mollusc Crepidula fornicata.
Developmental biology. 297(2):295-307 [PMID] 16919619.
2006
Dorso/ventral genes are asymmetrically expressed and involved in germ-layer demarcation during cnidarian gastrulation.
Current biology : CB. 16(5):499-505 [PMID] 16527745.
2006
Expression of otd orthologs in the amphipod crustacean, Parhyale hawaiensis.
Development genes and evolution. 216(10):581-95 [PMID] 16773341.
2006
Molecular evidence for deep evolutionary roots of bilaterality in animal development.
Proceedings of the National Academy of Sciences of the United States of America. 103(30):11195-200 [PMID] 16837574.
2005
A Clue to the Origin of the Bilateria?
Science (New York, N.Y.). 307(5708):353c-355c [PMID] 15664903.
2005
Genomic inventory and expression of Sox and Fox genes in the cnidarian Nematostella vectensis.
Development genes and evolution. 215(12):618-30 [PMID] 16193320.
2005
Neuroanatomy of sea spiders implies an appendicular origin of the protocerebral segment.
Nature. 437(7062):1144-8 [PMID] 16237442.
2005
The evolution of metazoan axial properties.
Nature reviews. Genetics. 6(12):917-27 [PMID] 16341072.
2005
Unexpected complexity of the Wnt gene family in a sea anemone.
Nature. 433(7022):156-60 [PMID] 15650739.
2005
vasa and nanos expression patterns in a sea anemone and the evolution of bilaterian germ cell specification mechanisms.
Evolution & development. 7(3):201-15 [PMID] 15876193.
2004
Fundamental properties of the spiralian developmental program are displayed by the basal nemertean Carinoma tremaphoros (Palaeonemertea, Nemertea).
Developmental biology. 267(2):342-60 [PMID] 15013798.
2004
Inductive interactions and embryonic equivalence groups in a basal metazoan, the ctenophore Mnemiopsis leidyi.
Evolution & development. 6(1):17-24 [PMID] 15108814.
2004
Investigating the origins of triploblasty: ‘mesodermal’ gene expression in a diploblastic animal, the sea anemone Nematostella vectensis (phylum, Cnidaria; class, Anthozoa).
Development (Cambridge, England). 131(10):2463-74 [PMID] 15128674.
2004
Origins of bilateral symmetry: Hox and dpp expression in a sea anemone.
Science (New York, N.Y.). 304(5675):1335-7 [PMID] 15131263.
2004
The ancestral role of COE genes may have been in chemoreception: evidence from the development of the sea anemone, Nematostella vectensis (Phylum Cnidaria; Class Anthozoa).
Development genes and evolution. 214(3):134-8 [PMID] 14752662.
2004
The cell lineage of the polyplacophoran, Chaetopleura apiculata: variation in the spiralian program and implications for molluscan evolution.
Developmental biology. 272(1):145-60 [PMID] 15242797.
2004
Vestigial prototroch in a basal nemertean, Carinoma tremaphoros (Nemertea; Palaeonemertea).
Evolution & development. 6(4):219-26 [PMID] 15230962.
2003
An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation.
Nature. 426(6965):446-50 [PMID] 14647383.
2003
Cephalopod Hox genes and the origin of morphological novelties.
Nature. 424(6952):1061-5 [PMID] 12944969.
2003
Early evolution of a homeobox gene: the parahox gene Gsx in the Cnidaria and the Bilateria.
Evolution & development. 5(4):331-45 [PMID] 12823450.
2003
Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?
Evolution & development. 5(4):372-8 [PMID] 12823453.
2003
Protein evolution: structure-function relationships of the oncogene beta-catenin in the evolution of multicellular animals.
Journal of experimental zoology. Part B, Molecular and developmental evolution. 295(1):25-44 [PMID] 12548541.
2002
Expression of the ctenophore Brain Factor 1 forkhead gene ortholog (ctenoBF-1) mRNA is restricted to the presumptive mouth and feeding apparatus: implications for axial organization in the Metazoa.
Development genes and evolution. 212(7):338-48 [PMID] 12185487.
2002
The origin of mesoderm in phoronids.
Developmental biology. 252(2):301-11 [PMID] 12482717.
2002
The Radiata and the evolutionary origins of the bilaterian body plan.
Molecular phylogenetics and evolution. 24(3):358-65 [PMID] 12220977.
2001
Deuterostome evolution: early development in the enteropneust hemichordate, Ptychodera flava.
Evolution & development. 3(6):375-90 [PMID] 11806633.
2001
Hox gene duplication and deployment in the annelid leech Helobdella.
Evolution & development. 3(3):145-53 [PMID] 11440249.
2001
Multiple inductive signals are involved in the development of the ctenophore Mnemiopsis leidyi.
Developmental biology. 238(1):40-6 [PMID] 11783992.
2001
The spatial and temporal expression of Ch-en, the engrailed gene in the polychaete Chaetopterus, does not support a role in body axis segmentation.
Developmental biology. 236(1):195-209 [PMID] 11456454.
2000
Combined-method phylogenetic analysis of Hox and ParaHox genes of the metazoa.
The Journal of experimental zoology. 288(2):175-91 [PMID] 10931500.
2000
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.
Nature. 408(6808):86-9 [PMID] 11081512.
2000
Expression patterns of anterior Hox genes in the polychaete Chaetopterus: correlation with morphological boundaries.
Developmental biology. 217(2):333-51 [PMID] 10625558.
2000
Regulation and regeneration in the ctenophore Mnemiopsis leidyi.
Developmental biology. 227(2):720-33 [PMID] 11071786.
2000
The unique developmental program of the acoel flatworm, Neochildia fusca.
Developmental biology. 220(2):285-95 [PMID] 10753516.
1999
Ancient origins of axial patterning genes: Hox genes and ParaHox genes in the Cnidaria.
Evolution & development. 1(1):16-23 [PMID] 11324016.
1999
Hox clusters. Size doesn’t matter.
Nature. 399(6738):730-1 [PMID] 10391234.
1999
Intracellular fate mapping in a basal metazoan, the ctenophore Mnemiopsis leidyi, reveals the origins of mesoderm and the existence of indeterminate cell lineages.
Developmental biology. 214(2):243-57 [PMID] 10525332.
1999
Larval ontogenetic stages of Chaetopterus: developmental heterochrony in the evolution of chaetopterid polychaetes.
The Biological bulletin. 197(3):319-31 [PMID] 10630333.
1998
Conservation of the spiralian developmental program: cell lineage of the nemertean, Cerebratulus lacteus.
Developmental biology. 201(2):253-69 [PMID] 9740663.
1998
Evolution of Cleavage Programs in Relationship to Axial Specification and Body Plan Evolution.
The Biological bulletin. 195(3):363-366 [DOI] 10.2307/1543148. [PMID] 28297612.
1998
The cell lineage of a polyclad turbellarian embryo reveals close similarity to coelomate spiralians.
Developmental biology. 204(1):111-23 [PMID] 9851846.
1998
The evolution of the Hox cluster: insights from outgroups.
Current opinion in genetics & development. 8(6):681-7 [PMID] 9914202.
1997
A survey of homeobox genes in Chaetopterus variopedatus and analysis of polychaete homeodomains.
Molecular phylogenetics and evolution. 7(3):331-45 [PMID] 9187092.
1997
Conserved anterior boundaries of Hox gene expression in the central nervous system of the leech Helobdella.
Developmental biology. 190(2):284-300 [PMID] 9344545.
1997
Experimental Analysis of Tentacle Formation in the Ctenophore Mnemiopsis leidyi.
The Biological bulletin. 193(2):245-247 [DOI] 10.1086/BBLv193n2p245. [PMID] 28575631.
1997
Homeoboxes in sea anemones (Cnidaria:Anthozoa): a PCR-based survey of Nematostella vectensis and Metridium senile.
The Biological bulletin. 193(1):62-76 [PMID] 9290214.
1997
Reassessing embryogenesis in the Ctenophora: the inductive role of e1 micromeres in organizing ctene row formation in the ‘mosaic’ embryo, Mnemiopsis leidyi.
Development (Cambridge, England). 124(10):1999-2006 [PMID] 9169846.
1997
Regulation and the modification of axial properties in partial embryos of the nemertean, Cerebratulus lacteus.
Development genes and evolution. 207(1):42-50 [DOI] 10.1007/s004270050090. [PMID] 20607479.
1997
The origin and evolution of animal appendages.
Proceedings of the National Academy of Sciences of the United States of America. 94(10):5162-6 [PMID] 9144208.
1996
Development and Regeneration of Comb Plates in the Ctenophore Mnemiopsis leidyi.
The Biological bulletin. 191(2):290-292 [DOI] 10.1086/BBLv191n2p290. [PMID] 29220260.
1996
Dual origins of mesoderm in a basal spiralian: cell lineage analyses in the polyclad turbellarian Hoploplana inquilina.
Developmental biology. 179(2):329-38 [PMID] 8903349.
1996
Homeobox genes in the Ctenophora: identification of paired-type and Hox homologues in the atentaculate ctenophore, Beroë ovata.
Molecular marine biology and biotechnology. 5(4):249-58 [PMID] 8983194.
1996
Isolation, characterization, and expression of Le-msx, a maternally expressed member of the msx gene family from the glossiphoniid leech, Helobdella.
Developmental dynamics : an official publication of the American Association of Anatomists. 207(4):404-19 [PMID] 8950515.
1996
Modified Spiral Cleavage: The Duet Cleavage Pattern and Early Blastomer Fates in the Acoel Turbellarian Neochildia fusca.
The Biological bulletin. 191(2):285-286 [DOI] 10.1086/BBLv191n2p285. [PMID] 29220272.
1996
The establishment of embryonic axial properties in the nemertean, Cerebratulus lacteus.
Developmental biology. 180(2):713-21 [PMID] 8954739.
1996
The Origins of Mesoderm in the Equal-Cleaving Nemertean Worm Cerebratulus lacteus.
The Biological bulletin. 191(2):286-288 [DOI] 10.1086/BBLv191n2p286. [PMID] 29220266.
1995
Axial Specification in a Basal Member of the Spiralian Glade: Lineage Relationships of the First Four Cells to the Larval Body Plan in the Polyclad Turbellarian Hoploplana inquilina.
The Biological bulletin. 189(2):194-195 [PMID] 27768490.
1995
Diagonal Development: Establishment of the Anal Axis in the Ctenophore Mnemiopsis leidyi.
The Biological bulletin. 189(2):190-192 [PMID] 27768492.
1995
Modifications of cell fate specification in equal-cleaving nemertean embryos: alternate patterns of spiralian development.
Development (Cambridge, England). 121(10):3175-85 [PMID] 7588052.
1995
The Experimental Alteration of Cell Lineages in the Nemertean Cerebratulus lacteus: Implications for the Precocious Establishment of Embryonic Axial Properties.
The Biological bulletin. 189(2):192-193 [PMID] 27768491.
1994
Inhibitory cell-cell interactions control development in the embryos of Cerebratulus lacteus.
The Biological bulletin. 187(2):238-9 [PMID] 7811796.
1991
Origin of segmental identity in the development of the leech nervous system.
Development (Cambridge, England). Supplement. Suppl 2:29-38 [PMID] 1688179.
1990
Interactions between adjacent ganglia bring about the bilaterally alternating differentiation of RAS and CAS neurons in the leech nerve cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 10(10):3183-93 [PMID] 2213140.
1990
Intrinsic segmental identity of segmental founder cells of the leech embryo.
Nature. 347(6294):672-4 [PMID] 2215696.
1990
Neuronal competition determines the spatial pattern of neuropeptide expression by identified neurons of the leech.
Developmental biology. 139(1):210-26 [PMID] 1691723.
1989
Segmental specificity and lateral asymmetry in the differentiation of developmentally homologous neurons during leech embryogenesis.
Developmental biology. 135(2):431-48 [PMID] 2776977.
1988
Developmental origin of segmental differences in the leech ectoderm: survival and differentiation of the distal tubule cell is determined by the host segment.
Developmental biology. 125(2):290-300 [PMID] 3338616.
1987
The organizing role of the D quadrant as revealed through the phenomenon of twinning in the polycheate Chætopterus variopedatus.
Roux's archives of developmental biology : the official organ of the EDBO. 196(8):499-510 [DOI] 10.1007/BF00399874. [PMID] 28305707.
1986
The ontogeny and maintenance of adult symmetry properties in the ctenophore, Mnemiopsis mccradyi.
Developmental biology. 118(2):556-76 [PMID] 2878844.
1984
Translational changes induced by 1-methyladenine in anucleate starfish oocytes.
Developmental biology. 101(2):512-5 [PMID] 6692993.
Independent innexin radiation shaped signaling in ctenophores
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Knockout of a single Sox gene resurrects an ancestral cell type in the sea anemone Nematostella vectensis
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Molecular patterning during the development ofPhoronopsis harmerireveals similarities to rhynchonelliform brachiopods
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Par protein localization during the early development ofMnemiopsis leidyisuggests different modes of epithelial organization in Metazoa
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β-catenin has an ancestral role in cell fate specification but not cell adhesion
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Grants

Mar 2022 ACTIVE
Transforming ctenophores into a tractable system for functional genomics
Role: Other
Funding: SOCIETY FOR DEVELOPMENTAL BIOLOGY
Dec 2021 ACTIVE
Reconstructing the development and functional architecture of the motor neural circuits of the last common animal ancestor
Role: Co-Investigator
Funding: Paul G. Allen Family Foundation
Nov 2020 – Sep 2021
Restoration of clam populations in the Indian River Lagoon for water quality improvement Year 2
Role: Faculty
Funding: IRL Council via US ENVIRONMENTAL PRO AGCY
Oct 2020 ACTIVE
URoL: MTM 1: Chemistry of cnidarian symbiosis: microbiomes role in association, morphogenesis, and protection
Role: Co-Investigator
Funding: NATL SCIENCE FOU
Jun 2020 – Apr 2021
Sea Turtle Transport Vehicle for The Sea Turtle Hospital at UF Whitney Laboratory
Role: Principal Investigator
Funding: SEA TURTLE CONSERVANCY
Jun 2019 – Dec 2021
DRPD-ROF2019: Biosynthetic Engineering of Materials and Composites
Role: Co-Project Director/Principal Investigator
Funding: UF RESEARCH
Jul 2018 ACTIVE
The spatial redeployment of conserved developmental signaling pathways fueled radical body plan evolution during the Cambrian explosion.
Role: Principal Investigator
Funding: NASA
Mar 2018 ACTIVE
A functional analysis of the evolution of metazoan cell polarity
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Aug 2017 – Jul 2018
FSML: Single Cell Marine Omics at the Whitney Marine Lab for
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Jul 2017 – Jul 2021
Evolution of a Multi-Functional Adhesion Module Necessary for Complex Multicellularity
Role: Principal Investigator
Funding: UNIV OF DENVER via NASA
Jan 2014 – Mar 2017
The cellular and molecular basis for the evolution of cell type complexity
Role: Principal Investigator
Funding: NASA STENNIS SPACE FLIGHT CTR

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