Lauren M McIntyre,
Professor
Department:
Molecular Genetics & Microbiology
Business Phone:
(352) 273-8024
Business Email:
mcintyre@ufl.edu
About Lauren M McIntyre
Fun Fact: I enjoy baking. It provides me with a steady supply of instantly gratifying successful work product. I use systems genetics to integrate genomic, transcriptomic, metabolomic and other “omic” scale data. I have a long-standing interest in sex-dimorphism in Drosophila focused on gene expression regulation and alternative splicing. More broadly, I am interested in the link between gene expression and chromatin, gene expression and organismal phenotype, and fundamentally how genetic variation percolates through the system. Using Drosophila as a springboard, the group works on developing statistical and computational methods that elucidate gene by environment interactions with applications in host-pathogen interactions, complex disease and climate change. We enthusiastically collaborate with others to address questions about the interplay between genetic variation and the environment and we are always looking for new questions and the next exciting technology.
Related Links:
Teaching Profile
Courses Taught
2020-2024
GMS6867 Big Data for the Biologist
2013-2019,2021-2025,2023-2025
GMS5905 Special Topics in Biomedical Sciences
2019
EGN4912 Engineering Directed Independent Research
2014-2015
GMS6231 Genomics and Bioinformatics
2008-2010,2012-2025,2022-2025,2025
PCB7922 Journal Colloquy in Plant Molecular and Cellular Biology
2011-2012
BMS6003 Genetics and Health
2010
GMS6290 Genetics/Genomics Program Graduate Seminar
2007-2008,2010
GMS6011 Mouse Genetics
2023-2024
GMS6905 Independent Studies in Medical Sciences
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-0077-3359
Publications
Academic Articles
2024
High-resolution methylome analysis uncovers stress-responsive genomic hotspots and drought-sensitive transposable element superfamilies in the clonal Lombardy poplar.
Journal of experimental botany.
75(18):5839-5856
[DOI] 10.1093/jxb/erae262.
[PMID] 38836523.
2024
Nucleotide-level distance metrics to quantify alternative splicing implemented in TranD.
Nucleic acids research.
52(5)
[DOI] 10.1093/nar/gkae056.
[PMID] 38340337.
2024
Science is a team sport: citations are how we recognize members of the team.
G3 (Bethesda, Md.).
14(7)
[DOI] 10.1093/g3journal/jkae102.
[PMID] 38975705.
2024
SQANTI-reads: a tool for the quality assessment of long read data in multi-sample lrRNA-seq experiments.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2024.08.23.609463.
[PMID] 39229095.
2024
SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms.
Nature methods.
21(5):793-797
[DOI] 10.1038/s41592-024-02229-2.
[PMID] 38509328.
2023
Estimating transcriptome complexities across eukaryotes.
BMC genomics.
24(1)
[DOI] 10.1186/s12864-023-09326-0.
[PMID] 37170194.
2023
Sex-biased expression is associated with chromatin state in D. melanogaster and D. simulans.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.01.13.523946.
[PMID] 36711631.
2023
Sex-Biased Expression Is Associated With Chromatin State in Drosophila melanogaster and Drosophila simulans.
Molecular biology and evolution.
40(5)
[DOI] 10.1093/molbev/msad078.
[PMID] 37116218.
2023
Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes.
Communications biology.
6(1)
[DOI] 10.1038/s42003-023-05327-7.
[PMID] 37758901.
2023
SQANTI3: curation of long-read transcriptomes for accurate identification of known and novel isoforms.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.05.17.541248.
[PMID] 37398077.
2023
Unknown Metabolite Identification Using Machine Learning Collision Cross-Section Prediction and Tandem Mass Spectrometry.
Analytical chemistry.
95(2):1047-1056
[DOI] 10.1021/acs.analchem.2c03749.
[PMID] 36595469.
2022
An anchored experimental design and meta-analysis approach to address batch effects in large-scale metabolomics.
Frontiers in molecular biosciences.
9
[DOI] 10.3389/fmolb.2022.930204.
[PMID] 36438654.
2022
GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease.
Scientific reports.
12(1)
[DOI] 10.1038/s41598-022-07238-9.
[PMID] 35228596.
2022
PaintOmics 4: new tools for the integrative analysis of multi-omics datasets supported by multiple pathway databases.
Nucleic acids research.
50(W1):W551-W559
[DOI] 10.1093/nar/gkac352.
[PMID] 35609982.
2022
The metabolome as a biomarker of aging in Drosophila melanogaster.
Aging cell.
21(2)
[DOI] 10.1111/acel.13548.
[PMID] 35019203.
2022
Variation in leaf transcriptome responses to elevated ozone corresponds with physiological sensitivity to ozone across maize inbred lines.
Genetics.
221(4)
[DOI] 10.1093/genetics/iyac080.
[PMID] 35579358.
2021
Long-Term Metabolomics Reference Material.
Analytical chemistry.
93(26):9193-9199
[DOI] 10.1021/acs.analchem.1c01294.
[PMID] 34156835.
2021
Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients.
Metabolites.
11(9)
[DOI] 10.3390/metabo11090645.
[PMID] 34564461.
2021
Power calculator for detecting allelic imbalance using hierarchical Bayesian model.
BMC research notes.
14(1)
[DOI] 10.1186/s13104-021-05851-x.
[PMID] 34838135.
2021
Risk Factors for Recurrent Staphylococcus aureus Bacteremia.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
72(11):1891-1899
[DOI] 10.1093/cid/ciaa801.
[PMID] 32564065.
2021
Testcrosses are an efficient strategy for identifying cis-regulatory variation: Bayesian analysis of allele-specific expression (BayesASE).
G3 (Bethesda, Md.).
11(5)
[DOI] 10.1093/g3journal/jkab096.
[PMID] 33772539.
2020
tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing.
Genome biology.
21(1)
[DOI] 10.1186/s13059-020-02028-w.
[PMID] 32423416.
2019
Fibrinogen binding is affected by amino acid substitutions in C-terminal repeat region of fibronectin binding protein A.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-48031-5.
[PMID] 31406152.
2019
Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone.
Journal of chemical information and modeling.
59(1):605-614
[DOI] 10.1021/acs.jcim.8b00745.
[PMID] 30602117.
2019
Uncovering hidden genetic variation in photosynthesis of field-grown maize under ozone pollution.
Global change biology.
25(12):4327-4338
[DOI] 10.1111/gcb.14794.
[PMID] 31571358.
2018
A Robust Methodology for Assessing Differential Homeolog Contributions to the Transcriptomes of Allopolyploids.
Genetics.
210(3):883-894
[DOI] 10.1534/genetics.118.301564.
[PMID] 30213855.
2018
Analysis of Gene Expression Variance in Schizophrenia Using Structural Equation Modeling.
Frontiers in molecular neuroscience.
11
[DOI] 10.3389/fnmol.2018.00192.
[PMID] 29942251.
2018
Direct Testing for Allele-Specific Expression Differences Between Conditions.
G3 (Bethesda, Md.).
8(2):447-460
[DOI] 10.1534/g3.117.300139.
[PMID] 29167272.
2018
Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data.
G3 (Bethesda, Md.).
8(9):2923-2940
[DOI] 10.1534/g3.118.200373.
[PMID] 30021829.
2018
Intergenerational environmental effects: functional signals in offspring transcriptomes and metabolomes after parental jasmonic acid treatment in apomictic dandelion.
The New phytologist.
217(2):871-882
[DOI] 10.1111/nph.14835.
[PMID] 29034954.
2018
SECIMTools: a suite of metabolomics data analysis tools.
BMC bioinformatics.
19(1)
[DOI] 10.1186/s12859-018-2134-1.
[PMID] 29678131.
2018
Variable selection in omics data: A practical evaluation of small sample sizes.
PloS one.
13(6)
[DOI] 10.1371/journal.pone.0197910.
[PMID] 29927942.
2017
A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design.
American journal of physiology. Heart and circulatory physiology.
312(6):H1215-H1223
[DOI] 10.1152/ajpheart.00016.2017.
[PMID] 28411229.
2017
Back to the Future: Multiparent Populations Provide the Key to Unlocking the Genetic Basis of Complex Traits.
Genetics.
206(2):527-529
[DOI] 10.1534/genetics.117.203265.
[PMID] 28592493.
2017
Back to the Future: Multiparent Populations Provide the Key to Unlocking the Genetic Basis of Complex Traits.
G3 (Bethesda, Md.).
7(6):1617-1618
[DOI] 10.1534/g3.117.042846.
[PMID] 28592643.
2017
Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes.
Genome research.
27(11):1807-1815
[DOI] 10.1101/gr.217984.116.
[PMID] 29025893.
2017
Elevated ozone reduces photosynthetic carbon gain by accelerating leaf senescence of inbred and hybrid maize in a genotype-specific manner.
Plant, cell & environment.
40(12):3088-3100
[DOI] 10.1111/pce.13075.
[PMID] 29044553.
2017
High-Throughput Phenotyping of Maize Leaf Physiological and Biochemical Traits Using Hyperspectral Reflectance.
Plant physiology.
173(1):614-626
[DOI] 10.1104/pp.16.01447.
[PMID] 28049858.
2017
Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing.
Viruses.
9(8)
[DOI] 10.3390/v9080226.
[PMID] 28812996.
2017
SHH Protein Variance in the Limb Bud Is Constrained by Feedback Regulation and Correlates with Altered Digit Patterning.
G3 (Bethesda, Md.).
7(3):851-858
[DOI] 10.1534/g3.116.033019.
[PMID] 28131983.
2017
UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.
Diabetes.
66(7):2033-2043
[DOI] 10.2337/db16-1023.
[PMID] 28607106.
2016
Buffering of Genetic Regulatory Networks in Drosophila melanogaster.
Genetics.
203(3):1177-90
[DOI] 10.1534/genetics.116.188797.
[PMID] 27194752.
2016
Neurons That Underlie Drosophila melanogaster Reproductive Behaviors: Detection of a Large Male-Bias in Gene Expression in fruitless-Expressing Neurons.
G3 (Bethesda, Md.).
6(8):2455-65
[DOI] 10.1534/g3.115.019265.
[PMID] 27247289.
2016
Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol.
Metabolomics : Official journal of the Metabolomic Society.
12(10)
[DOI] 10.1007/s11306-016-1098-2.
[PMID] 28217401.
2016
RNA-seq analysis of impact of PNN on gene expression and alternative splicing in corneal epithelial cells.
Molecular vision.
22:40-60
[PMID] 26900324.
2015
The Wright stuff: reimagining path analysis reveals novel components of the sex determination hierarchy in Drosophila melanogaster.
BMC systems biology.
9
[DOI] 10.1186/s12918-015-0200-0.
[PMID] 26335107.
2014
A flexible Bayesian method for detecting allelic imbalance in RNA-seq data.
BMC genomics.
15(1)
[DOI] 10.1186/1471-2164-15-920.
[PMID] 25339465.
2014
A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells.
BMC genomics.
15(1)
[DOI] 10.1186/1471-2164-15-668.
[PMID] 25106478.
2014
GENETICS and G3: community-driven science, community-driven journals.
G3 (Bethesda, Md.).
4(9):1567-8
[DOI] 10.1534/g3.114.013680.
[PMID] 25237108.
2014
GENETICS and G3: community-driven science, community-driven journals.
Genetics.
198(1):1-2
[DOI] 10.1534/genetics.114.169151.
[PMID] 25236444.
2014
LANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complex.
PLoS pathogens.
10(7)
[DOI] 10.1371/journal.ppat.1004240.
[PMID] 25033463.
2014
Leveraging biological replicates to improve analysis in ChIP-seq experiments.
Computational and structural biotechnology journal.
9
[DOI] 10.5936/csbj.201401002.
[PMID] 24688750.
2014
What the X has to do with it: differences in regulatory variability between the sexes in Drosophila simulans.
Genome biology and evolution.
6(4):818-29
[DOI] 10.1093/gbe/evu060.
[PMID] 24696400.
2013
Consistent errors in first strand cDNA due to random hexamer mispriming.
PloS one.
8(12)
[DOI] 10.1371/journal.pone.0085583.
[PMID] 24386481.
2013
Effects of Root-Knot Nematode Parasitism On Host Gene Silencing
Phytopathology.
103
2013
Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains.
BMC genomics.
14
[DOI] 10.1186/1471-2164-14-659.
[PMID] 24074028.
2013
Plants know where it hurts: root and shoot jasmonic acid induction elicit differential responses in Brassica oleracea.
PloS one.
8(6)
[DOI] 10.1371/journal.pone.0065502.
[PMID] 23776489.
2013
Purification of transcripts and metabolites from Drosophila heads.
Journal of visualized experiments : JoVE.
(73)
[DOI] 10.3791/50245.
[PMID] 23524378.
2012
Ago HITS-CLIP expands understanding of Kaposi’s sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.
PLoS pathogens.
8(8)
[DOI] 10.1371/journal.ppat.1002884.
[PMID] 22927820.
2012
Allelic imbalance in Drosophila hybrid heads: exons, isoforms, and evolution.
Molecular biology and evolution.
29(6):1521-32
[DOI] 10.1093/molbev/msr318.
[PMID] 22319150.
2012
Enhanced expression of Pctk1, Tcf12 and Ccnd1 in hippocampus of rats: Impact on cognitive function, synaptic plasticity and pathology.
Neurobiology of learning and memory.
97(1):69-80
[DOI] 10.1016/j.nlm.2011.09.006.
[PMID] 21982980.
2012
Facilitating discovery: the role of Society Journals in collaborative science.
Genetics.
190(2):285-6
[DOI] 10.1534/genetics.111.137935.
[PMID] 22345602.
2012
Facilitating discovery: the role of society journals in collaborative science.
G3 (Bethesda, Md.).
2(2):151-2
[DOI] 10.1534/g3.111.001859.
[PMID] 22384392.
2012
Genetic variation in the Yolk protein expression network of Drosophila melanogaster: sex-biased negative correlations with longevity.
Heredity.
109(4):226-34
[DOI] 10.1038/hdy.2012.34.
[PMID] 22760232.
2012
Genotype-phenotype mapping in a post-GWAS world.
Trends in genetics : TIG.
28(9):421-6
[DOI] 10.1016/j.tig.2012.06.003.
[PMID] 22818580.
2012
Setting the standard: a special focus on genomic selection in GENETICS and G3.
Genetics.
190(4):1151-2
[DOI] 10.1534/genetics.112.139907.
[PMID] 22491887.
2012
Setting the Standard: A Special Focus on Genomic Selection in GENETICS and G3.
G3 (Bethesda, Md.).
2(4)
[DOI] 10.1534/g3.112.002295.
[PMID] 22540032.
2012
The chemical interactions underlying tomato flavor preferences.
Current biology : CB.
22(11):1035-9
[DOI] 10.1016/j.cub.2012.04.016.
[PMID] 22633806.
2012
The Influence of Parasitic Interactions On Host Gene Silencing
Phytopathology.
102
2012
Transcriptional network structure has little effect on the rate of regulatory evolution in yeast.
Molecular biology and evolution.
29(8):1899-905
[DOI] 10.1093/molbev/msq283.
[PMID] 20966117.
2011
Experimental challenge of cattle with German atypical bovine spongiform encephalopathy (BSE) isolates.
Journal of toxicology and environmental health. Part A.
74(2-4):103-9
[DOI] 10.1080/15287394.2011.529060.
[PMID] 21218339.
2011
Expression of defense genes in Drosophila evolves under a different selective regime from expression of other genes.
Evolution; international journal of organic evolution.
65(4):1068-78
[DOI] 10.1111/j.1558-5646.2010.01197.x.
[PMID] 21108635.
2011
Generalized shrinkage F-like statistics for testing an interaction term in gene expression analysis in the presence of heteroscedasticity.
BMC bioinformatics.
12
[DOI] 10.1186/1471-2105-12-427.
[PMID] 22044602.
2011
Partitioning transcript variation in Drosophila: abundance, isoforms, and alleles.
G3 (Bethesda, Md.).
1(6):427-36
[DOI] 10.1534/g3.111.000596.
[PMID] 22384353.
2011
Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices.
Proceedings of the National Academy of Sciences of the United States of America.
108(45):18372-7
[DOI] 10.1073/pnas.1109071108.
[PMID] 22025727.
2011
Potential associations between severity of infection and the presence of virulence-associated genes in clinical strains of Staphylococcus aureus.
PloS one.
6(4)
[DOI] 10.1371/journal.pone.0018673.
[PMID] 21541311.
2011
RNA-seq: technical variability and sampling.
BMC genomics.
12
[DOI] 10.1186/1471-2164-12-293.
[PMID] 21645359.
2011
Transcriptome profiling of embryonic development rate in rainbow trout advanced backcross introgression lines.
Marine biotechnology (New York, N.Y.).
13(2):215-31
[DOI] 10.1007/s10126-010-9283-1.
[PMID] 20352270.
2010
Comparison between NuGEN’s WT-Ovation Pico and one-direct amplification systems.
Journal of biomolecular techniques : JBT.
21(3):141-7
[PMID] 20808643.
2010
Data: the foundation of science.
Genetics.
184(1)
[DOI] 10.1534/genetics.109.108498.
[PMID] 20061563.
2010
Direct mapping of density response in a population of B73 x Mo17 recombinant inbred lines of maize (Zea Mays L.).
Heredity.
104(6):583-99
[DOI] 10.1038/hdy.2009.140.
[PMID] 19888291.
2010
Epistasis: obstacle or advantage for mapping complex traits?
PloS one.
5(8)
[DOI] 10.1371/journal.pone.0012264.
[PMID] 20865037.
2010
Maize Grain Yield Responses To Plant Height Variability Resulting From Crop Rotation and Tillage System in a Long-Term Experiment
Soil & Tillage Research.
106(2):227-240
[DOI] 10.1016/j.still.2009.12.006.
2010
Phenotypic plasticity in cell walls of maize brown midrib mutants is limited by lignin composition.
Journal of experimental botany.
61(9):2479-90
[DOI] 10.1093/jxb/erq093.
[PMID] 20410320.
2010
SOLiD sequencing of four Vibrio vulnificus genomes enables comparative genomic analysis and identification of candidate clade-specific virulence genes.
BMC genomics.
11
[DOI] 10.1186/1471-2164-11-512.
[PMID] 20863407.
2009
Allele-specific expression assays using Solexa.
BMC genomics.
10
[DOI] 10.1186/1471-2164-10-422.
[PMID] 19740431.
2009
Defining gene and QTL networks.
Current opinion in plant biology.
12(2):241-6
[DOI] 10.1016/j.pbi.2009.01.003.
[PMID] 19196544.
2009
Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster.
BMC genomics.
10
[DOI] 10.1186/1471-2164-10-124.
[PMID] 19317915.
2009
Regulatory divergence in Drosophila melanogaster and D. simulans, a genomewide analysis of allele-specific expression.
Genetics.
183(2):547-61, 1SI
[DOI] 10.1534/genetics.109.105957.
[PMID] 19667135.
2009
Sex-specific splicing in Drosophila: widespread occurrence, tissue specificity and evolutionary conservation.
Genetics.
181(2):421-34
[DOI] 10.1534/genetics.108.096743.
[PMID] 19015538.
2008
Cis and trans regulatory effects contribute to natural variation in transcriptome of Drosophila melanogaster.
Molecular biology and evolution.
25(1):101-10
[PMID] 17998255.
2008
Evolution of gene expression in the Drosophila olfactory system.
Molecular biology and evolution.
25(6):1081-92
[DOI] 10.1093/molbev/msn055.
[PMID] 18296696.
2008
Powdery mildew induces defense-oriented reprogramming of the transcriptome in a susceptible but not in a resistant grapevine.
Plant physiology.
146(1):236-49
[PMID] 17993546.
2008
Successful range-expanding plants experience less above-ground and below-ground enemy impact.
Nature.
456(7224):946-8
[DOI] 10.1038/nature07474.
[PMID] 19020504.
2007
Differential expression of genes important for adaptation in Capsella bursa-pastoris (Brassicaceae).
Plant physiology.
145(1):160-73
[PMID] 17631524.
2007
Mapping reciprocal effects and interactions with plant density stress in Zea mays L.
Heredity.
99(1):14-30
[PMID] 17473872.
2007
Potential associations between hematogenous complications and bacterial genotype in Staphylococcus aureus infection.
The Journal of infectious diseases.
196(5):738-47
[PMID] 17674317.
2007
Simpler mode of inheritance of transcriptional variation in male Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America.
104(47):18577-82
[PMID] 18003923.
2006
Changes in skeletal muscle gene expression following clenbuterol administration.
BMC genomics.
7
[PMID] 17181869.
2006
Mapping density response in maize: a direct approach for testing genotype and treatment interactions.
Genetics.
173(1):331-48
[PMID] 16489238.
2006
Sex-specific expression of alternative transcripts in Drosophila.
Genome biology.
7(8)
[PMID] 16934145.
2006
Using mating designs to uncover QTL and the genetic architecture of complex traits.
Heredity.
96(2):139-49
[PMID] 16304603.
2005
Genetic architecture of two fitness-related traits in Drosophila melanogaster: ovariole number and thorax length.
Genetica.
125(2-3):211-22
[PMID] 16247693.
2005
Identification of co-regulated transcripts affecting male body size in Drosophila.
Genome biology.
6(6)
[PMID] 15960805.
2005
Model selection in binary trait locus mapping.
Genetics.
170(3):1281-97
[PMID] 15834149.
2005
Nematode-induced changes of transporter gene expression in Arabidopsis roots.
Molecular plant-microbe interactions : MPMI.
18(12):1247-57
[PMID] 16478044.
2005
Sex- and segment-specific modulation of gene expression profiles in Drosophila.
Developmental biology.
288(2):528-44
[PMID] 16269142.
2004
Additivity and trans-acting effects on gene expression in male Drosophila simulans.
Genetics.
168(3):1413-20
[PMID] 15579694.
2004
Common pattern of evolution of gene expression level and protein sequence in Drosophila.
Molecular biology and evolution.
21(7):1308-17
[PMID] 15034135.
2004
Differential gene expression in response to hydrogen peroxide and the putative PerR regulon of Synechocystis sp. strain PCC 6803.
Journal of bacteriology.
186(11):3331-45
[PMID] 15150218.
2004
Expression profile analysis of wild-type and fcc1 mutant strains of Fusarium verticillioides during fumonisin biosynthesis.
Fungal genetics and biology : FG & B.
41(6):647-56
[PMID] 15121086.
2004
Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila.
Proceedings of the National Academy of Sciences of the United States of America.
101(18):7034-9
[PMID] 15118106.
2004
Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein.
The Journal of infectious diseases.
190(6):1140-9
[PMID] 15319865.
2004
Using alpha wisely: improving power to detect multiple QTL.
Statistical applications in genetics and molecular biology.
3
[PMID] 16646787.
2003
Fatal outcome of bacteraemic patients caused by infection with staphylokinase-deficient Staphylococcus aureus strains.
Journal of medical microbiology.
52(Pt 10):919-923
[DOI] 10.1099/jmm.0.05145-0.
[PMID] 12972589.
2003
Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana.
Nature biotechnology.
21(10):1215-21
[PMID] 12949535.
2003
Intersection tests for single marker QTL analysis can be more powerful than two marker QTL analysis.
BMC genetics.
4
[PMID] 12816551.
2003
Microarray analysis of the genome-wide response to iron deficiency and iron reconstitution in the cyanobacterium Synechocystis sp. PCC 6803.
Plant physiology.
132(4):1825-39
[PMID] 12913140.
2002
Carotid endarterectomy and race: do clinical indications and patient preferences account for differences?
Stroke.
33(12):2936-43
[PMID] 12468794.
2002
Combining mapping and arraying: An approach to candidate gene identification.
Proceedings of the National Academy of Sciences of the United States of America.
99(23):14903-6
[PMID] 12415114.
2002
Cross-species hybridisation of pig RNA to human nylon microarrays.
BMC genomics.
3(1)
[PMID] 12354330.
2002
Evidence for an evolutionarily conserved interaction between cell wall biosynthesis and flowering in maize and sorghum.
BMC evolutionary biology.
2
[PMID] 11835688.
2002
Prognostic significance of molecular genetic aberrations on chromosome segment 11p15.5 in non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
20(5):1353-60
[PMID] 11870179.
2002
The maize Brown midrib1 locus affects cell wall composition and plant development in a dose-dependent manner.
Heredity.
88(6):450-7
[PMID] 12180087.
2001
Dementia with Lewy bodies and Alzheimer’s disease.
Acta neuropathologica.
102(6):621-6
[PMID] 11761723.
2001
Detection and localization of a single binary trait locus in experimental populations.
Genetical research.
78(1):79-92
[PMID] 11556139.
2001
Measuring patient expectations: does the instrument affect satisfaction or expectations?
Medical care.
39(1):100-8
[PMID] 11176547.
2001
Rater agreement and utility of the mutagen-induced chromosome damage assay.
Anticancer research.
21(1B):605-9
[PMID] 11299813.
2001
The self-reported functional measure: Predictive validity for health care utilization in multiple sclerosis and spinal cord injury.
Archives of physical medicine and rehabilitation.
82(5):613-8
[PMID] 11346837.
2000
Circumventing multiple testing: a multilocus Monte Carlo approach to testing for association.
Genetic epidemiology.
19(1):18-29
[PMID] 10861894.
2000
Early onset baldness and prostate cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
9(3):325-8
[PMID] 10750672.
2000
Evaluation of molecular techniques to biotype Giardia duodenalis collected during an outbreak.
The Journal of parasitology.
86(1):172-7
[PMID] 10701587.
2000
Factors considered important at the end of life by patients, family, physicians, and other care providers.
JAMA.
284(19):2476-82
[PMID] 11074777.
2000
In search of a good death: observations of patients, families, and providers.
Annals of internal medicine.
132(10):825-32
[PMID] 10819707.
2000
In vitro resistance to thrombin-induced platelet microbicidal protein in isolates of Staphylococcus aureus from endocarditis patients correlates with an intravascular device source.
The Journal of infectious diseases.
182(4):1251-4
[PMID] 10979928.
2000
Incidence of stroke and season of the year: evidence of an association.
American journal of epidemiology.
152(6):558-64
[PMID] 10997546.
2000
Maximizing the motivational impact of feedback of lung cancer susceptibility on smokers’ desire to quit.
Journal of health communication.
5(3):229-41
[PMID] 11185023.
2000
Racial variation in wanting and obtaining mental health services among women veterans in a primary care clinic.
Journal of the National Medical Association.
92(5):231-6
[PMID] 10881472.
1999
Disability fingerprints: patterns of disability in spinal cord injury and multiple sclerosis differ.
The journals of gerontology. Series A, Biological sciences and medical sciences.
54(12):M613-20
[PMID] 10647967.
1999
Race, presenting signs and symptoms, use of carotid artery imaging, and appropriateness of carotid endarterectomy.
Stroke.
30(7):1350-6
[PMID] 10390306.
1999
The effect of orchiectomy on lung cancer survival.
Anticancer research.
19(6C):5567-70
[PMID] 10697618.
1999
The validity in persons with spinal cord injury of a self-reported functional measure derived from the functional independence measure.
Spine.
24(6):539-43; discussion 543
[PMID] 10101817.
1999
Time to flowering in brown midrib mutants of maize: an alternative approach to the analysis of developmental traits.
Heredity.
83 ( Pt 2):171-8
[PMID] 10469205.
1999
Validation of a Trauma Questionnaire in veteran women.
Journal of general internal medicine.
14(3):186-9
[PMID] 10203625.
1998
Neuropathological and neuropsychological changes in “normal” aging: evidence for preclinical Alzheimer disease in cognitively normal individuals.
Journal of neuropathology and experimental neurology.
57(12):1168-74
[PMID] 9862640.
1998
The reliability of a self-reported measure of disease, impairment, and function in persons with spinal cord dysfunction.
Archives of physical medicine and rehabilitation.
79(4):378-87
[PMID] 9552102.
1998
Understanding racial variation in the use of carotid endarterectomy: the role of aversion to surgery.
Journal of the National Medical Association.
90(1):25-33
[PMID] 9473926.
1997
Hardy-Weinberg testing for continuous data.
Genetics.
147(4):1965-75
[PMID] 9409851.
1995
Are we ready for diphtheria? A report from the Diphtheria Diagnostic Workshop, Atlanta, 11 and 12 July 1994.
The Journal of infectious diseases.
171(4):765-7
[PMID] 7706801.
Grants
Jun 2022
ACTIVE
Noncoding RNAs in gamma-Herpesvirus Biology and AIDS Malignancies
Role: Other
Funding: NATL INST OF HLTH NCI
Jan 2021
– Dec 2024
Rapid evolution of pigmentation in D. melanogaster: from cis regulation to phenotype
Role: Principal Investigator
Funding: UNIV OF PENNSYLVANIA
via NATL INST OF HLTH NIGMS
Sep 2018
– Aug 2023
Allele Specific Regulation of Context Specific GRN
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Sep 2018
– Jun 2023
Genetics and quantum chemistry as tools for unknown metabolite identification
Role: Principal Investigator
Funding: UNIVERSITY OF GEORGIA
via NATL INST OF HLTH NIEHS
Jun 2018
– May 2023
Immune Function and the Progression to Type 1 Diabetes
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Apr 2018
– Feb 2023
Critical role for alternative splicing in conferring risk for type 1 diabetes
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDDK
Sep 2017
– Aug 2020
Galaxy platform for integrative metabolomics and transcriptomics analysis
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Feb 2017
– Jan 2022
Noncoding RNAs in gamma-Herpesvirus Biology and AIDS Malignancies
Role: Faculty
Funding: NATL INST OF HLTH NCI
Dec 2016
– Jun 2018
Novel solutions to increase crop productivity
Role: Principal Investigator
Funding: BAYER CROPSCIENCE LP
Dec 2016
– Jul 2021
Systematic identification of functional T1D-associated non-coding SNPs using genetic, transcriptomic and epigenetic methods
Role: Co-Investigator
Funding: UNIV OF VIRGINIA
via NATL INST OF HLTH NIDDK
Jun 2014
– Apr 2020
Molecular binding reaction that initiates Staphylococcus aureus infections of car
Role: Principal Investigator
Funding: OHIO STATE UNIV
via NATL INST OF HLTH NHLBI
Sep 2013
– Aug 2019
Southeast Resource Center for Integrated Metabolomics (SECIM)
Role: Other
Funding: NATL INST OF HLTH NIDDK
Jan 2013
– Dec 2019
Genetic and Genomic Approaches to Understand and Improve Maize Responses to Ozone
Role: Principal Investigator
Funding: UNIV OF ILLINOIS URBANA-CHAMPAIGN
via NATL SCIENCE FOU
Sep 2012
– Jun 2017
Quantitative Comparisons between genotypes and model species
Role: Principal Investigator
Funding: NATL INST OF HLTH NIGMS
Contact Details
Phones:
- Business:
- (352) 273-8024
Emails:
- Business:
- mcintyre@ufl.edu
Addresses:
- Business Mailing:
-
PO BOX 103610
DEPT OF MOLECULAR GENETICS AND MICROBIOLOGY
GAINESVILLE FL 326103610 - Business Street:
-
1376 MOWRY ROAD
GAINESVILLE FL 326100001