David C Bloom,
Hazel Kitzman Professor Of Genetics And Chair, College Of Medicine, Department Of Molecular Genetics And Microbiology
Department:
Molecular Genetics & Microbiology
Business Phone:
(352) 273-9524
Business Email:
dbloom@ufl.edu
About David C Bloom
Teaching Profile
Courses Taught
2020-2023
GMS7133 Advanced Molecular Virology
2020
BMS6634 GI and Hepatology
2008,2010-2023
GMS6196 Virology Journal Club
2013-2023
GMS6035 Advanced Virology II: RNA Viruses
2012-2019,2021-2022
GMS5905 Special Topics in Biomedical Sciences
2019
EGN4912 Engineering Directed Independent Research
2013,2015-2018
BCH7412 Epigenetics of Human Disease and Development
2018
GMS7980 Research for Doctoral Dissertation
2018
GMS6034 Advanced Virology I: Genetics and RNA
2018
BMS6300 Fund Micro and Immuno
2006-2007
GMS6181 Spec Topics Microbiol
2023
PHA6183 Pharmaceutical Gene Delivery
2023
BMS6635 Derm and Msk
2023
BMS6020 Clinical Neuroscience
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0001-5935-8494
Publications
2023
HSV-1 LAT Promoter Deletion Viruses Exhibit Strain-Specific and LAT-Dependent Epigenetic Regulation of Latent Viral Genomes in Human Neurons
Journal of Virology.
97(2)
[DOI] 10.1128/jvi.01935-22.
[PMID] 36722973.
2023
Treatment of infection and inflammation associated with COVID-19, multi-drug resistant pneumonia and fungal sinusitis by nebulizing a nanosilver solution.
Nanomedicine : nanotechnology, biology, and medicine.
48
[DOI] 10.1016/j.nano.2023.102654.
[PMID] 36646192.
2023
Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-28691-0.
[PMID] 36717567.
2023
Virology under the Microscope—a Call for Rational Discourse
mSphere.
8(2)
[DOI] 10.1128/msphere.00034-23.
[PMID] 36700653.
2023
Virology under the Microscope—a Call for Rational Discourse
Journal of Virology.
97(2)
[DOI] 10.1128/jvi.00089-23.
[PMID] 36700640.
2023
Virology under the Microscope—a Call for Rational Discourse
mBio.
14(1)
[DOI] 10.1128/mbio.00188-23.
[PMID] 36700642.
2022
A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response.
Microbiology spectrum.
10(4)
[DOI] 10.1128/spectrum.00593-22.
[PMID] 35730940.
2022
Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication.
Virology.
569:13-28
[DOI] 10.1016/j.virol.2022.01.002.
[PMID] 35219218.
2022
Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo.
Viruses.
14(5)
[DOI] 10.3390/v14050909.
[PMID] 35632655.
2022
Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides.
Frontiers in immunology.
13
[DOI] 10.3389/fimmu.2022.902956.
[PMID] 35799776.
2022
Signaling Pathway Reporter Screen with SARS-CoV-2 Proteins Identifies nsp5 as a Repressor of p53 Activity.
Viruses.
14(5)
[DOI] 10.3390/v14051039.
[PMID] 35632779.
2022
The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids.
Cells.
11(22)
[DOI] 10.3390/cells11223539.
[PMID] 36428968.
2022
Transneuronal tracing to map connectivity in injured and transplanted spinal networks.
Experimental neurology.
351
[DOI] 10.1016/j.expneurol.2022.113990.
[PMID] 35085573.
2022
Variations in Aspects of Neural Precursor Cell Neurogenesis in a Human Model of HSV-1 Infection.
Organogenesis.
18(1)
[DOI] 10.1080/15476278.2022.2055354.
[PMID] 35384798.
2021
Correction for Zheng et al., “Patterns of Herpes Simplex Virus 1 Infection in Neural Progenitor Cells”.
Journal of virology.
95(4)
[DOI] 10.1128/JVI.02189-20.
[PMID] 33509936.
2021
Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation In Vivo.
Journal of virology.
95(4)
[DOI] 10.1128/JVI.02179-20.
[PMID] 33208453.
2021
Modeling Aβ42 Accumulation in Response to Herpes Simplex Virus 1 Infection: 2D or 3D?
Journal of virology.
95(5)
[DOI] 10.1128/JVI.02219-20.
[PMID] 33268524.
2020
Antiviral activity of 1,4-disubstituted-1,2,3-triazoles against HSV-1 in vitro.
Antiviral therapy.
25(8):399-410
[DOI] 10.3851/IMP3387.
[PMID] 33705354.
2020
Deletion of Herpes Simplex Virus 1 MicroRNAs miR-H1 and miR-H6 Impairs Reactivation.
Journal of virology.
94(15)
[DOI] 10.1128/JVI.00639-20.
[PMID] 32295910.
2020
Herpes Simplex Virus 1 Strains 17syn+ and KOS(M) Differ Greatly in Their Ability To Reactivate from Human Neurons In Vitro.
Journal of virology.
94(15)
[DOI] 10.1128/JVI.00796-20.
[PMID] 32461310.
2020
Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines.
Vaccines.
8(2)
[DOI] 10.3390/vaccines8020230.
[PMID] 32443425.
2020
Patterns of Herpes Simplex Virus 1 Infection in Neural Progenitor Cells.
Journal of virology.
94(16)
[DOI] 10.1128/JVI.00994-20.
[PMID] 32493817.
2020
Perillyl alcohol and perillic acid exert efficient action upon HSV-1 maturation and release of infective virus.
Antiviral therapy.
25(1):1-11
[DOI] 10.3851/IMP3315.
[PMID] 31099756.
2019
Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 Latency In Vitro.
Journal of virology.
93(6)
[DOI] 10.1128/JVI.02210-18.
[PMID] 30602607.
2019
Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells.
Journal of virology.
93(9)
[DOI] 10.1128/JVI.00111-19.
[PMID] 30787148.
2019
Peripheral AAV Injection for Retrograde Transduction of Dorsal Root and Trigeminal Ganglia.
Methods in molecular biology (Clifton, N.J.).
1950:237-247
[DOI] 10.1007/978-1-4939-9139-6_13.
[PMID] 30783977.
2019
Personalized viral genomic investigation of herpes simplex virus 1 perinatal viremic transmission with dual fatality.
Cold Spring Harbor molecular case studies.
5(6)
[DOI] 10.1101/mcs.a004382.
[PMID] 31582464.
2019
The CCCTC Binding Factor, CTRL2, Modulates Heterochromatin Deposition and the Establishment of Herpes Simplex Virus 1 Latency In Vivo.
Journal of virology.
93(13)
[DOI] 10.1128/JVI.00415-19.
[PMID] 30996085.
2019
Virtual screening identified compounds that bind to cyclin dependent kinase 2 and prevent herpes simplex virus type 1 replication and reactivation in neurons.
Antiviral research.
172
[DOI] 10.1016/j.antiviral.2019.104621.
[PMID] 31634495.
2018
Depletion of the Insulator Protein CTCF Results in Herpes Simplex Virus 1 Reactivation In Vivo.
Journal of virology.
92(11)
[DOI] 10.1128/JVI.00173-18.
[PMID] 29514910.
2018
Generation of Three-Dimensional Human Neuronal Cultures: Application to Modeling CNS Viral Infections
Current Stem Cell Research & Therapy.
9(1)
[DOI] 10.1186/s13287-018-0881-6.
[PMID] 29751846.
2018
Genome-Wide Surveillance of Genital Herpes Simplex Virus Type 1 From Multiple Anatomic Sites Over Time.
The Journal of infectious diseases.
218(4):595-605
[DOI] 10.1093/infdis/jiy216.
[PMID] 29920588.
2018
Immunization by Replication-Competent Controlled Herpesvirus Vectors.
Journal of virology.
92(16)
[DOI] 10.1128/JVI.00616-18.
[PMID] 29899091.
2018
In Vivo Knockdown of the Herpes Simplex Virus 1 Latency-Associated Transcript Reduces Reactivation from Latency.
Journal of virology.
92(16)
[DOI] 10.1128/JVI.00812-18.
[PMID] 29875240.
2018
R430: A potent inhibitor of DNA and RNA viruses
Scientific Reports.
8(1)
[DOI] 10.1038/s41598-018-33904-y.
[PMID] 30413769.
2018
Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation.
International journal of molecular sciences.
19(10)
[DOI] 10.3390/ijms19102961.
[PMID] 30274169.
2018
The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication.
Journal of virology.
92(6)
[DOI] 10.1128/JVI.01884-17.
[PMID] 29263259.
2017
Comparison of three cell-based drug screening platforms for HSV-1 infection
Antiviral Research.
142:136-140
[DOI] 10.1016/j.antiviral.2017.03.016.
[PMID] 28342892.
2017
Development of Recombinant HSV-Based Vaccine Vectors.
Methods in molecular biology (Clifton, N.J.).
1581:55-78
[DOI] 10.1007/978-1-4939-6869-5_4.
[PMID] 28374243.
2017
HSV1 latent transcription and non-coding RNA: A critical retrospective.
Journal of neuroimmunology.
308:65-101
[DOI] 10.1016/j.jneuroim.2017.03.002.
[PMID] 28363461.
2017
Opinion: Why we need a centralized repository for isotopic data.
Proceedings of the National Academy of Sciences of the United States of America.
114(12):2997-3001
[DOI] 10.1073/pnas.1701742114.
[PMID] 28325883.
2017
Reliable Detection of Herpes Simplex Virus Sequence Variation by High-Throughput Resequencing.
Viruses.
9(8)
[DOI] 10.3390/v9080226.
[PMID] 28812996.
2016
Adeno-associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Coinfected with Herpes Simplex Virus 1 following Peripheral Inoculation.
Journal of virology.
90(17):7894-901
[DOI] 10.1128/JVI.01028-16.
[PMID] 27334582.
2016
Alphaherpesvirus Latency: A Dynamic State of Transcription and Reactivation.
Advances in virus research.
94:53-80
[DOI] 10.1016/bs.aivir.2015.10.001.
[PMID] 26997590.
2016
Herpes simplex virus type-1: replication, latency, reactivation and its antiviral targets.
Antiviral therapy.
21(4):277-86
[DOI] 10.3851/IMP3018.
[PMID] 26726828.
2016
Simultaneous visualization of two Citrus tristeza virus genotypes provides new insights into the structure of multi-component virus populations in a host.
Virology.
491:10-9
[DOI] 10.1016/j.virol.2016.01.017.
[PMID] 26874013.
2016
The importance of digitized biocollections as a source of trait data and a new VertNet resource.
Database : the journal of biological databases and curation.
2016
[DOI] 10.1093/database/baw158.
[PMID] 28025346.
2015
A Genomic Approach to Unravel Host-Pathogen Interaction in Chelonians: The Example of Testudinid Herpesvirus 3.
PloS one.
10(8)
[DOI] 10.1371/journal.pone.0134897.
[PMID] 26244892.
2015
A novel approach for addressing diseases not yielding to effective vaccination? Immunization by replication-competent controlled virus.
Expert review of vaccines.
14(5):637-51
[DOI] 10.1586/14760584.2015.1013941.
[PMID] 25676927.
2015
Broad-spectrum non-nucleoside inhibitors of human herpesviruses.
Antiviral research.
121:16-23
[DOI] 10.1016/j.antiviral.2015.06.005.
[PMID] 26079681.
2015
Inhibition of H3K27me3-specific histone demethylases JMJD3 and UTX blocks reactivation of herpes simplex virus 1 in trigeminal ganglion neurons.
Journal of virology.
89(6):3417-20
[DOI] 10.1128/JVI.03052-14.
[PMID] 25552720.
2015
Replication-Competent Controlled Herpes Simplex Virus.
Journal of virology.
89(20):10668-79
[DOI] 10.1128/JVI.01667-15.
[PMID] 26269179.
2014
Leveraging biological replicates to improve analysis in ChIP-seq experiments.
Computational and structural biotechnology journal.
9
[DOI] 10.5936/csbj.201401002.
[PMID] 24688750.
2013
Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture.
Journal of virology.
87(12):6589-603
[DOI] 10.1128/JVI.00504-13.
[PMID] 23536669.
2013
Role of polycomb proteins in regulating HSV-1 latency.
Viruses.
5(7):1740-57
[DOI] 10.3390/v5071740.
[PMID] 23860385.
2012
Darwin Core: an evolving community-developed biodiversity data standard.
PloS one.
7(1)
[DOI] 10.1371/journal.pone.0029715.
[PMID] 22238640.
2012
From documents to datasets: A MediaWiki-based method of annotating and extracting species observations in century-old field notebooks.
ZooKeys.
(209):235-53
[DOI] 10.3897/zookeys.209.3247.
[PMID] 22859891.
2012
LAT region factors mediating differential neuronal tropism of HSV-1 and HSV-2 do not act in trans.
PloS one.
7(12)
[DOI] 10.1371/journal.pone.0053281.
[PMID] 23300908.
2012
Regulated protein expression for in vivo gene therapy for neurological disorders: progress, strategies, and issues.
Neurobiology of disease.
48(2):212-21
[DOI] 10.1016/j.nbd.2012.03.001.
[PMID] 22426391.
2012
Respiratory function following bilateral mid-cervical contusion injury in the adult rat.
Experimental neurology.
235(1):197-210
[DOI] 10.1016/j.expneurol.2011.09.024.
[PMID] 21963673.
2011
Three Group Risk Stratification for Pediatric Brain Stem Gliomas Treated With Radiotherapy Based On Clinical Presentation and Imaging Characteristics
Pediatric Blood & Cancer.
57:720-721
2010
Braun Enteroenterostomy Is Associated With Reduced Delayed Gastric Emptying and Early Resumption of Oral Feeding Following Pancreaticoduodenectomy
Journal of Surgical Oncology.
101(5):351-355
[DOI] 10.1002/jso.21490.
[PMID] 20112274.
2010
Epigenetic regulation of latent HSV-1 gene expression.
Biochimica et biophysica acta.
1799(3-4):246-56
[DOI] 10.1016/j.bbagrm.2009.12.001.
[PMID] 20045093.
2009
A limited innate immune response is induced by a replication-defective herpes simplex virus vector following delivery to the murine central nervous system.
Journal of neurovirology.
15(5-6):411-24
[DOI] 10.3109/13550280903473452.
[PMID] 20095947.
2009
Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome.
Gene therapy.
16(9):1122-9
[DOI] 10.1038/gt.2009.83.
[PMID] 19571888.
2009
The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency.
Journal of virology.
83(16):8173-81
[DOI] 10.1128/JVI.00686-09.
[PMID] 19515780.
2008
Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat.
The Journal of comparative neurology.
511(5):692-709
[DOI] 10.1002/cne.21864.
[PMID] 18924146.
2008
Different tropism of adenoviruses and adeno-associated viruses to corneal cells: implications for corneal gene therapy.
Molecular vision.
14:2087-96
[PMID] 19023450.
2008
During herpes simplex virus type 1 infection of rabbits, the ability to express the latency-associated transcript increases latent-phase transcription of lytic genes.
Journal of virology.
82(12):6056-60
[DOI] 10.1128/JVI.02661-07.
[PMID] 18400860.
2008
Fak and Igf-Ir Interact To Provide Survival Signals in Human Pancreatic Adenocarcinoma Cells
Carcinogenesis.
29(6):1096-1107
[DOI] 10.1093/carcin/bgn026.
[PMID] 18263593.
2008
Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia.
Molecular vision.
14:1209-21
[PMID] 18615202.
2008
Ranavirus Infection of Free-Ranging and Captive Box Turtles and Tortoises in the United States
.
44:851-863
2008
Ranavirus infection of free-ranging and captive box turtles and tortoises in the United States.
Journal of wildlife diseases.
44(4):851-63
[PMID] 18957641.
2008
Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA.
Journal of virology.
82(15):7467-74
[DOI] 10.1128/JVI.02720-07.
[PMID] 18508896.
2007
In vivo changes in the patterns of chromatin structure associated with the latent herpes simplex virus type 1 genome in mouse trigeminal ganglia can be detected at early times after butyrate treatment.
Journal of virology.
81(23):13248-53
[PMID] 17881451.
2006
A chromatin insulator-like element in the herpes simplex virus type 1 latency-associated transcript region binds CCCTC-binding factor and displays enhancer-blocking and silencing activities.
Journal of virology.
80(5):2358-68
[PMID] 16474142.
2006
Deacetylation of the herpes simplex virus type 1 latency-associated transcript (LAT) enhancer and a decrease in LAT abundance precede an increase in ICP0 transcriptional permissiveness at early times postexplant.
Journal of virology.
80(4):2063-8
[PMID] 16439563.
2006
Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic mice.
Journal of virology.
80(19):9414-23
[PMID] 16973547.
2005
Assessment of recovery in the hemiparkinson rat: drug-induced rotation is inadequate.
Physiology & behavior.
84(4):525-35
[PMID] 15811387.
2005
Assessment of viral and non-viral gene transfer into adult rat brains using HSV-1, calcium phosphate and PEI-based methods.
Folia morphologica.
64(3):130-44
[PMID] 16228947.
2005
Transfection of tyrosine kinase deleted FGF receptor-1 into rat brain substantia nigra reduces the number of tyrosine hydroxylase expressing neurons and decreases concentration levels of striatal dopamine.
Brain research. Molecular brain research.
139(2):361-6
[PMID] 16039006.
2004
Experimental transmission of a herpesvirus in Greek tortoises (Testudo graeca).
Veterinary pathology.
41(1):50-61
[PMID] 14715968.
2004
HSV LAT and neuronal survival.
International reviews of immunology.
23(1-2):187-98
[PMID] 14690860.
2004
Specific histone tail modification and not DNA methylation is a determinant of herpes simplex virus type 1 latent gene expression.
Journal of virology.
78(3):1139-49
[PMID] 14722269.
2004
The herpes simplex virus type 1 latency-associated transcript (LAT) enhancer/rcr is hyperacetylated during latency independently of LAT transcription.
Journal of virology.
78(22):12508-18
[PMID] 15507638.
2004
Wide variations in herpes simplex virus type 1 inoculum dose and latency-associated transcript expression phenotype do not alter the establishment of latency in the rabbit eye model.
Journal of virology.
78(10):5038-44
[PMID] 15113885.
2003
Herpes simplex virus-1 and varicella-zoster virus latency in ganglia.
Journal of neurovirology.
9(2):194-204
[PMID] 12707850.
2003
Overlapping subdeletions within a 348-bp in the 5′ exon of the LAT region that facilitates epinephrine-induced reactivation of HSV-1 in the rabbit ocular model do not further define a functional element.
Virology.
312(1):151-8
[PMID] 12890628.
2002
Altering the expression kinetics of VP5 results in altered virulence and pathogenesis of herpes simplex virus type 1 in mice.
Journal of virology.
76(5):2199-205
[PMID] 11836397.
2002
The region of the HSV-1 latency-associated transcript required for epinephrine-induced reactivation in the rabbit does not include the 2.0-kb intron.
Virology.
292(1):59-69
[PMID] 11878908.
1993
A revised HindIII map and sequence analysis of a large ‘left-hand’ non-essential region of the rabbit poxvirus genome.
Virus research.
28(2):125-40
[PMID] 8391191.
1991
Identification and characterization of two nonessential regions of the rabbitpox virus genome involved in virulence.
Journal of virology.
65(3):1530-42
[PMID] 1847470.
1991
The nature of naturally occurring mutations in the hemagglutinin gene of vaccinia virus and the sequence of immediately adjacent genes.
Virus genes.
5(3):235-42
[PMID] 1771764.
Grants
Jul 2021
– Dec 2021
Assessment of antiviral activity of non-toxic polymer-based disinfectant
Role: Principal Investigator
Funding: EXION LABS
Apr 2021
– May 2021
Assessment of Antiviral Activity of Silver Mask Material
Role: Principal Investigator
Funding: CYPRESS RIVER ADVISORS
Dec 2020
ACTIVE
Basic Microbiology and Infectious Disease
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Sep 2020
– Dec 2020
Assessment of Reactivation of HSV Oncolytic Vectors
Role: Principal Investigator
Funding: VIROGIN BIOTECH CANADA
Jul 2020
– Aug 2020
Analysis of Hypochlorous Acid Wound Cleanser for Anti-Viral Activity
Role: Principal Investigator
Funding: URGO MEDICAL
Jul 2020
ACTIVE
Effects of HSV-1 infection on neural progenitor cell biology in vitro and in vivo
Role: Principal Investigator
Funding: UNIV OF PITTSBURGH
via NATL INST OF HLTH NINDS
Apr 2020
– Jun 2020
Analysis of Nanocrystalline Silver for Anti-viral Activity
Role: Principal Investigator
Funding: UNIV OF ALBERTA
Jan 2020
– Sep 2021
RNA polymerase II occupancy and activity in HSV-infected post-mitotic neurons
Role: Principal Investigator
Funding: LOUISIANA STATE UNIV
via NATL INST OF HLTH NIAID
Aug 2019
– Dec 2020
Phenotypic analyses of HSV-1 miRNAs: H1, H6, & H8
Role: Other
Funding: NATL INST OF HLTH NIAID
Mar 2019
ACTIVE
Molecular Genetics of HSV Reactivation
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Nov 2018
ACTIVE
CTCF-mediated HSV-1 gene expression during latency and reactivation
Role: Principal Investigator
Funding: UNIV OF WISCONSIN MADISON
via NATL INST OF HLTH NIAID
Oct 2018
– May 2020
Analysis of the specific effects of Tranexamic Acid on HSV infection
Role: Principal Investigator
Funding: ANTI PLASMIN TECHNOLOGIES
Sep 2016
– Aug 2018
Analysis of human-specific aspects of HSV-1 latency in human iPSC-derived neurons
Role: Principal Investigator
Funding: UNIV OF PITTSBURGH
via NATL INST OF HLTH NINDS
Jun 2016
– May 2018
OR-DRPD-ROF2016: Visualizing viral entry into neurons and the brain: Changing the paradigm
Role: Co-Investigator
Funding: UF DSR OPPORTUNITY FUND
Jan 2016
– Dec 2016
Vector-delivered CRISPR/Cas as a cure for HSV-1 induced keratitis
Role: Principal Investigator
Funding: EDITAS MEDICINE
via NATL INST OF HLTH NIAID
Sep 2015
– Aug 2016
The Role of the LAT Locus in HSV-1 Infection of Human Skin Xenografts in Vivo
Role: Principal Investigator
Funding: STANFORD UNIV
via NATL INST OF HLTH NIAID
Jul 2015
– Jun 2018
Function of histone chaperones in HSV-1 chromatin sturcture during latency, establishing maintenance and reactivation
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Jun 2015
– Jun 2016
Effect of spaceflight on Herpesvirus genome stability and diversity
Role: Principal Investigator
Funding: NASA
Aug 2014
– Jul 2020
Basic Microbiology and Infectious Disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Aug 2014
– Apr 2017
Cytotoxic lymphocytes and HSV-1 corneal lesions
Role: Principal Investigator
Funding: UNIV OF PITTSBURGH
via NATL INST OF HLTH
Jan 2014
– Jan 2017
Determination of Roles of Microgravity and Ionizing Radiation on the Reactivation of Epstein-Barr Virus in vitro
Role: Principal Investigator
Funding: NASA STENNIS SPACE FLIGHT CTR
Jul 2013
ACTIVE
Evaluation of the suitability of SafeSwitch-controlled HSV as anti-herpetic"vaccines" or as immunization platform
Role: Principal Investigator
Funding: HSF PHARMACEUTICALS SA
Jan 2012
– Dec 2017
Regulation of lytic and latent infection by HSV-1 encoded miRNAs
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jul 2010
– Oct 2020
HSV-1 Research Program – UFF Transfer Account
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2010
– Oct 2020
HSV-2 Research Program – UFF Transfer Account
Role: Principal Investigator
Funding: UF FOUNDATION
Contact Details
Phones:
- Business:
- (352) 273-9524
Emails:
- Business:
- dbloom@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100266
GAINESVILLE FL 32610 - Business Street:
-
1200 NEWELL DR
GAINESVILLE FL 32610